Reaction Details |
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Target | Dual specificity protein phosphatase 23 |
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Ligand | BDBM50054344 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Inhibition Assay |
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IC50 | 2300±200 nM |
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Citation | Zhang, Z; Zeng, L Hydroxyindole carboxylic acid based inhibitors for oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) US Patent US9522881 Publication Date 12/20/2016 |
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More Info.: | Get all data from this article, Assay Method |
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Dual specificity protein phosphatase 23 |
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Name: | Dual specificity protein phosphatase 23 |
Synonyms: | DUS23_HUMAN | DUSP23 | Dual specificity protein phosphatase 23 | Dual specificity protein phosphatase 23 (VHZ) | LDP-3 | LDP3 | Low molecular mass dual specificity phosphatase 3 | VH1-like phosphatase Z | VHZ |
Type: | Enzyme |
Mol. Mass.: | 16592.49 |
Organism: | Homo sapiens (Human) |
Description: | Q9BVJ7 |
Residue: | 150 |
Sequence: | MGVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHR
LRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGD
AIAEIRRLRPGSIETYEQEKAVFQFYQRTK
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BDBM50054344 |
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n/a |
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Name | BDBM50054344 |
Synonyms: | CHEMBL3319356 | US9522881, 11a-1 L97M74 | US9844535, ID 11a-1 L97M74 |
Type | Small organic molecule |
Emp. Form. | C28H20IN3O5S |
Mol. Mass. | 637.445 |
SMILES | Cn1c(c(I)c2cc(C(O)=O)c(O)cc12)-c1cccc(NC(=O)C(=O)Nc2ccc(cc2)-c2ccsc2)c1 |
Structure |
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