Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Non-receptor tyrosine-protein kinase TYK2 [888-1187] | ||
Ligand | BDBM410160 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Caliper mobility shift assay | ||
IC50 | >10000±n/a nM | ||
Citation | Gauvry, N; Tahtaoui, C; Furet, P; Ducray, P Heterocyclyl-substituted cyclohexylsulfonamides as JAK inhibitors US Patent US10370375 Publication Date 8/6/2019 | ||
More Info.: | Get all data from this article, Assay Method | ||
Non-receptor tyrosine-protein kinase TYK2 [888-1187] | |||
Name: | Non-receptor tyrosine-protein kinase TYK2 [888-1187] | ||
Synonyms: | Non-receptor tyrosine-protein kinase TYK2 (aa 888-1187) | TYK2 | TYK2 (aa 888-1187) | TYK2_HUMAN | ||
Type: | Protein | ||
Mol. Mass.: | 34527.73 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P29597[888-1187] | ||
Residue: | 300 | ||
Sequence: |
| ||
BDBM410160 | |||
n/a | |||
Name | BDBM410160 | ||
Synonyms: | US10370375, Example 8 | ||
Type | Small organic molecule | ||
Emp. Form. | C14H20N4O2S2 | ||
Mol. Mass. | 340.464 | ||
SMILES | CNS(=O)(=O)C[C@H]1CCC(CC1)Nc1ncnc2sccc12 |r,wD:6.5,(4.29,4.1,;4.29,5.64,;2.96,6.41,;1.63,7.18,;4.29,7.18,;2.96,4.87,;1.63,4.1,;.29,4.87,;-1.04,4.1,;-1.04,2.56,;.29,1.79,;1.63,2.56,;-2.38,1.79,;-2.38,.25,;-3.71,-.52,;-3.71,-2.06,;-2.38,-2.83,;-1.04,-2.06,;.42,-2.54,;1.33,-1.29,;.42,-.05,;-1.04,-.52,)| | ||
Structure |