| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM256645 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Activity Assay |
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| IC50 | >100000±n/a nM |
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| Citation |  Matsumoto, S; Hattori, Y; Toyofuku, M; Morimoto, S; Daini, M; Kojima, T; Kaku, T; Ito, M Cyclopropanamine compound and use thereof US Patent US10414761 Publication Date 9/17/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
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| Type: | Protein |
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| Mol. Mass.: | 58768.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27338 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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| BDBM256645 |
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| n/a |
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| Name | BDBM256645 |
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| Synonyms: | US10053456, 24 | US10414761, Example 24 | US10968213, Example 24 | US9487511, 24 | US9718814, 24 | US9920047, 24 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H28F2N2O2S |
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| Mol. Mass. | 398.51 |
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| SMILES | FC1(F)CCC(CC1)NC(=O)c1csc(c1)C1CC1NCC1CCOCC1 |
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| Structure | 
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