| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Toll-like receptor 9 |
|---|
| Ligand | BDBM273537 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Biological Assay |
|---|
| IC50 | 3024±n/a nM |
|---|
| Citation |  Dyckman, AJ; Dodd, DS; Mussari, CP; Pasunoori, L; Kumar, SR [1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds US Patent US10478424 Publication Date 11/19/2019 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Toll-like receptor 9 |
|---|
| Name: | Toll-like receptor 9 |
|---|
| Synonyms: | CD_antigen: CD289 | TLR9 | TLR9_HUMAN |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 115889.91 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9NR96 |
|---|
| Residue: | 1032 |
|---|
| Sequence: | MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAA
PRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFL
AVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYY
KNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDL
ANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLN
ASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSF
GSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYV
DLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLS
RNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHS
FTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSL
RALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRL
RDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGF
FSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAA
VPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCG
WDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRG
RWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLE
DRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHF
YNRNFCQGPTAE
|
|
|
|---|
| BDBM273537 |
|---|
| n/a |
|---|
| Name | BDBM273537 |
|---|
| Synonyms: | US10071079, Example 320 | US10478424, Example 320 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H36N6O |
|---|
| Mol. Mass. | 484.6357 |
|---|
| SMILES | CC(C)c1c([nH]c2ccc(cc12)C1CCN(CC(=O)N(C)C)CC1)-c1cc(C2CC2)c2ncnn2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
