| Reaction Details |
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 | Report a problem with these data |
| Target | Interleukin-6 |
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| Ligand | BDBM423509 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Interleukin 6 Induction Assay |
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| EC50 | 14.0±n/a nM |
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| Citation |  He, L; Gangwar, S; Poudel, YB; Sivaprakasam, P Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor US Patent US10508115 Publication Date 12/17/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Interleukin-6 |
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| Name: | Interleukin-6 |
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| Synonyms: | B-cell stimulatory factor 2 | BSF-2 | CDF | CTL differentiation factor | Hybridoma growth factor | IFN-beta-2 | IFNB2 | IL-6 | IL6 | IL6_HUMAN | Interferon beta-2 |
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| Type: | n/a |
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| Mol. Mass.: | 23717.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P05231 |
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| Residue: | 212 |
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| Sequence: | MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI
LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
|
|
|
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| BDBM423509 |
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| n/a |
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| Name | BDBM423509 |
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| Synonyms: | US10508115, Compound Id-03 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H32N8O4 |
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| Mol. Mass. | 520.5835 |
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| SMILES | CCCCOc1nc(N)c2nc(O)n(Cc3ccc(Oc4ccc(CNC5CCOCC5)nc4)nc3)c2n1 |
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| Structure | 
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