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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase BTK | ||
| Ligand | BDBM165582 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Btk Enzyme Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 0.14±n/a nM | ||
| Comments | extracted | ||
| Citation |  Liu, Q; Watterson, SH; Ahmad, S Indole carboxamide compounds US Patent US9688629 Publication Date 6/27/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase BTK | |||
| Name: | Tyrosine-protein kinase BTK | ||
| Synonyms: | AGMX1 | ATK | Agammaglobulinaemia tyrosine kinase | Agammaglobulinemia tyrosine kinase | B cell progenitor kinase | B-cell progenitor kinase | BPK | BTK | BTK_HUMAN | Bruton tyrosine kinase | Tyrosine Kinase BTK | Tyrosine-protein kinase (BTK) | Tyrosine-protein kinase BTK (BTK) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 76289.95 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q06187 | ||
| Residue: | 659 | ||
| Sequence: |
| ||
| BDBM165582 | |||
| n/a | |||
| Name | BDBM165582 | ||
| Synonyms: | US10604504, Example 193 | US11623921, Example 193 | US9688629, 193 | US9802915, Example 193 | US9920031, Example 193 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H20FN3O2 | ||
| Mol. Mass. | 377.4115 | ||
| SMILES | Cc1[nH]c2c(cc(F)c(-c3cccc4N(CCc34)C(=O)C=C)c2c1C)C(N)=O |(-5.51,2.3,;-3.97,2.3,;-3.06,3.54,;-1.6,3.07,;-.26,3.84,;1.07,3.07,;1.07,1.53,;2.4,.76,;-.26,.76,;-.26,-.78,;-1.6,-1.55,;-1.6,-3.09,;-.26,-3.86,;1.07,-3.09,;2.53,-3.57,;3.44,-2.32,;2.53,-1.08,;1.07,-1.55,;2.93,-5.06,;1.84,-6.15,;4.42,-5.46,;5.51,-4.37,;-1.6,1.53,;-3.06,1.05,;-3.52,-.28,;-.26,5.38,;1.07,6.15,;-1.6,6.15,)| | ||
| Structure | 
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