| Reaction Details |
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 | Report a problem with these data |
| Target | Eukaryotic translation initiation factor 4E |
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| Ligand | BDBM451153 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | thermodynamic (Steady State Affinity) binding analysis |
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| Kd | 6500±n/a nM |
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| Citation |  Barnes-Seeman, D; Cohen, SL; Diener, JL; Gampe, C; Roache, J; White, A; Williams, S; Yuan, J; Zecri, F 3′ end caps, 5′ end caps and combinations thereof for therapeutic RNA US Patent US10676499 Publication Date 6/9/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Eukaryotic translation initiation factor 4E |
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| Name: | Eukaryotic translation initiation factor 4E |
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| Synonyms: | EIF4E | EIF4EL1 | EIF4F | Eukaryotic translation initation factor | Eukaryotic translation initiation factor 4E (eIF4E) | Eukaryotic translation initiation factor 4E/Eukaryotic translation initiation factor 4E-binding protein 1 | IF4E_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 25095.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06730 |
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| Residue: | 217 |
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| Sequence: | MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
QRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIG
RVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
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| BDBM451153 |
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| n/a |
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| Name | BDBM451153 |
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| Synonyms: | US10676499, Example 42 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25N6O11PS |
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| Mol. Mass. | 636.528 |
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| SMILES | COC(=O)c1ccsc1NC(=O)c1cccc(C[n+]2cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c3nc(N)nc([O-])c23)c1 |r| |
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| Structure | 
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