Compile Data Set for Download or QSAR

Found 1604 hits with Last Name = 'zecri' and Initial = 'f'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451155 (US10676499, Example 49) Show SMILES Cc1ccccc1-c1ccc(C[n+]2cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c3nc(N)nc([O-])c23)cc1 |r| Show InChI InChI=1S/C24H26N5O8P/c1-13-4-2-3-5-16(13)15-8-6-14(7-9-15)10-28-12-29(21-18(28)22(32)27-24(25)26-21)23-20(31)19(30)17(37-23)11-36-38(33,34)35/h2-9,12,17,19-20,23,30-31H,10-11H2,1H3,(H4-,25,26,27,32,33,34,35)/t17-,19-,20-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451145 (US10676499, Example 17) Show SMILES Nc1nc([O-])c2[n+](Cc3cc4ccccc4s3)cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C19H20N5O8PS/c20-19-21-16-13(17(27)22-19)23(6-10-5-9-3-1-2-4-12(9)34-10)8-24(16)18-15(26)14(25)11(32-18)7-31-33(28,29)30/h1-5,8,11,14-15,18,25-26H,6-7H2,(H4-,20,21,22,27,28,29,30)/t11-,14-,15-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451159 (US10676499, Example 57) Show SMILES Nc1nc([O-])c2[n+](Cc3ccc(cc3)-c3cccs3)cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C21H22N5O8PS/c22-21-23-18-15(19(29)24-21)25(8-11-3-5-12(6-4-11)14-2-1-7-36-14)10-26(18)20-17(28)16(27)13(34-20)9-33-35(30,31)32/h1-7,10,13,16-17,20,27-28H,8-9H2,(H4-,22,23,24,29,30,31,32)/t13-,16-,17-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451148 (US10676499, Example 29) Show SMILES Nc1nc([O-])c2[n+](Cc3cccc(OC(F)(F)F)c3)cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C18H19F3N5O9P/c19-18(20,21)35-9-3-1-2-8(4-9)5-25-7-26(14-11(25)15(29)24-17(22)23-14)16-13(28)12(27)10(34-16)6-33-36(30,31)32/h1-4,7,10,12-13,16,27-28H,5-6H2,(H4-,22,23,24,29,30,31,32)/t10-,12-,13-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451158 (US10676499, Example 55) Show SMILES Nc1nc([O-])c2[n+](Cc3ccc(c(Cl)c3)-c3ccccc3)cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C23H23ClN5O8P/c24-15-8-12(6-7-14(15)13-4-2-1-3-5-13)9-28-11-29(20-17(28)21(32)27-23(25)26-20)22-19(31)18(30)16(37-22)10-36-38(33,34)35/h1-8,11,16,18-19,22,30-31H,9-10H2,(H4-,25,26,27,32,33,34,35)/t16-,18-,19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451147 (US10676499, Example 26) Show SMILES COc1cccc(C[n+]2cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c3nc(N)nc([O-])c23)c1 |r| Show InChI InChI=1S/C18H22N5O9P/c1-30-10-4-2-3-9(5-10)6-22-8-23(15-12(22)16(26)21-18(19)20-15)17-14(25)13(24)11(32-17)7-31-33(27,28)29/h2-5,8,11,13-14,17,24-25H,6-7H2,1H3,(H4-,19,20,21,26,27,28,29)/t11-,13-,14-,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451144 (US10676499, Example 1) Show SMILES Nc1nc([O-])c2[n+](Cc3ccc(cc3)-c3ccccc3)cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C23H24N5O8P/c24-23-25-20-17(21(31)26-23)27(10-13-6-8-15(9-7-13)14-4-2-1-3-5-14)12-28(20)22-19(30)18(29)16(36-22)11-35-37(32,33)34/h1-9,12,16,18-19,22,29-30H,10-11H2,(H4-,24,25,26,31,32,33,34)/t16-,18-,19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451150 (US10676499, Example 33) Show SMILES Nc1nc([O-])c2[n+](Cc3cccc(Oc4ccccc4)c3)cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C23H24N5O9P/c24-23-25-20-17(21(31)26-23)27(10-13-5-4-8-15(9-13)36-14-6-2-1-3-7-14)12-28(20)22-19(30)18(29)16(37-22)11-35-38(32,33)34/h1-9,12,16,18-19,22,29-30H,10-11H2,(H4-,24,25,26,31,32,33,34)/t16-,18-,19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451146 (US10676499, Example 18) Show SMILES CO[C@H]1[C@@H](O)[C@H](COP(O)(O)=O)O[C@@H]1n1c[n+](CCOc2ccc(Cl)cc2)c2c([O-])nc(N)nc12 |r| Show InChI InChI=1S/C19H23ClN5O9P/c1-31-15-14(26)12(8-33-35(28,29)30)34-18(15)25-9-24(13-16(25)22-19(21)23-17(13)27)6-7-32-11-4-2-10(20)3-5-11/h2-5,9,12,14-15,18,26H,6-8H2,1H3,(H4-,21,22,23,27,28,29,30)/t12-,14-,15-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451156 (US10676499, Example 53) Show SMILES COc1cc(ccc1C[n+]1cn([C@H]2O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]2O)c2nc(N)nc([O-])c12)-c1ccccc1 |r| Show InChI InChI=1S/C24H26N5O9P/c1-36-16-9-14(13-5-3-2-4-6-13)7-8-15(16)10-28-12-29(21-18(28)22(32)27-24(25)26-21)23-20(31)19(30)17(38-23)11-37-39(33,34)35/h2-9,12,17,19-20,23,30-31H,10-11H2,1H3,(H4-,25,26,27,32,33,34,35)/t17-,19-,20-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451160 (US10676499, Example 58) Show SMILES Nc1nc([O-])c2[n+](Cc3ccc(cc3)-c3ccccc3F)cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C23H23FN5O8P/c24-15-4-2-1-3-14(15)13-7-5-12(6-8-13)9-28-11-29(20-17(28)21(32)27-23(25)26-20)22-19(31)18(30)16(37-22)10-36-38(33,34)35/h1-8,11,16,18-19,22,30-31H,9-10H2,(H4-,25,26,27,32,33,34,35)/t16-,18-,19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451151 (US10676499, Example 40) Show SMILES COC(=O)c1sccc1NC(=O)c1cccc(C[n+]2cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c3nc(N)nc([O-])c23)c1 |r| Show InChI InChI=1S/C24H25N6O11PS/c1-39-23(35)18-13(5-6-43-18)26-20(33)12-4-2-3-11(7-12)8-29-10-30(19-15(29)21(34)28-24(25)27-19)22-17(32)16(31)14(41-22)9-40-42(36,37)38/h2-7,10,14,16-17,22,31-32H,8-9H2,1H3,(H5-,25,26,27,28,33,34,35,36,37,38)/t14-,16-,17-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451157 (US10676499, Example 54) Show SMILES Nc1nc([O-])c2[n+](Cc3ccc(cc3F)-c3ccccc3)cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C23H23FN5O8P/c24-15-8-13(12-4-2-1-3-5-12)6-7-14(15)9-28-11-29(20-17(28)21(32)27-23(25)26-20)22-19(31)18(30)16(37-22)10-36-38(33,34)35/h1-8,11,16,18-19,22,30-31H,9-10H2,(H4-,25,26,27,32,33,34,35)/t16-,18-,19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.78E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451154 (US10676499, Example 43) Show SMILES Nc1nc([O-])c2[n+](Cc3cccc(OCc4ccccc4)c3)cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C24H26N5O9P/c25-24-26-21-18(22(32)27-24)28(10-15-7-4-8-16(9-15)36-11-14-5-2-1-3-6-14)13-29(21)23-20(31)19(30)17(38-23)12-37-39(33,34)35/h1-9,13,17,19-20,23,30-31H,10-12H2,(H4-,25,26,27,32,33,34,35)/t17-,19-,20-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451153 (US10676499, Example 42) Show SMILES COC(=O)c1ccsc1NC(=O)c1cccc(C[n+]2cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c3nc(N)nc([O-])c23)c1 |r| Show InChI InChI=1S/C24H25N6O11PS/c1-39-23(35)13-5-6-43-21(13)27-19(33)12-4-2-3-11(7-12)8-29-10-30(18-15(29)20(34)28-24(25)26-18)22-17(32)16(31)14(41-22)9-40-42(36,37)38/h2-7,10,14,16-17,22,31-32H,8-9H2,1H3,(H5-,25,26,27,28,33,34,35,36,37,38)/t14-,16-,17-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451152 (US10676499, Example 41) Show SMILES Nc1nc([O-])c2[n+](Cc3cccc(c3)C(=O)Oc3c(Cl)cccc3Cl)cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C24H22Cl2N5O10P/c25-13-5-2-6-14(26)19(13)41-23(35)12-4-1-3-11(7-12)8-30-10-31(20-16(30)21(34)29-24(27)28-20)22-18(33)17(32)15(40-22)9-39-42(36,37)38/h1-7,10,15,17-18,22,32-33H,8-9H2,(H4-,27,28,29,34,36,37,38)/t15-,17-,18-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM451149 (US10676499, Example 32) Show SMILES Nc1nc([O-])c2[n+](Cc3ccccc3CS(=O)(=O)c3ccccc3)cn([C@H]3O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]3O)c2n1 |r| Show InChI InChI=1S/C24H26N5O10PS/c25-24-26-21-18(22(32)27-24)28(13-29(21)23-20(31)19(30)17(39-23)11-38-40(33,34)35)10-14-6-4-5-7-15(14)12-41(36,37)16-8-2-1-3-9-16/h1-9,13,17,19-20,23,30-31H,10-12H2,(H4-,25,26,27,32,33,34,35)/t17-,19-,20-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9.36E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...				US Patent US10676499 (2020) BindingDB Entry DOI: 10.7270/Q2K64N44
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM341005 (US9763952, Example E1 | US9763952, Example F1 | {(...) Show SMILES COc1ncc(cc1C)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)OC(C)(C)C)cc12 |r| Show InChI InChI=1S/C23H30N4O5/c1-15-10-16(12-25-21(15)29-5)27-8-9-30-19-13-24-20(11-18(19)27)31-17-6-7-26(14-17)22(28)32-23(2,3)4/h10-13,17H,6-9,14H2,1-5H3/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204087 (US9539260, F4 | US9763952, Example F4) Show SMILES COc1ncc(cc1C#N)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)C3CCOCC3)cc12 |r| Show InChI InChI=1S/C24H27N5O5/c1-31-23-17(12-25)10-18(13-27-23)29-6-9-33-21-14-26-22(11-20(21)29)34-19-2-5-28(15-19)24(30)16-3-7-32-8-4-16/h10-11,13-14,16,19H,2-9,15H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204089 (US9539260, F6 | US9763952, Example F6) Show SMILES Cc1cc(cnc1S(C)(=O)=O)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)C3CCOCC3)cc12 |r| Show InChI InChI=1S/C24H30N4O6S/c1-16-11-18(13-26-23(16)35(2,30)31)28-7-10-33-21-14-25-22(12-20(21)28)34-19-3-6-27(15-19)24(29)17-4-8-32-9-5-17/h11-14,17,19H,3-10,15H2,1-2H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204090 (US9539260, F7 | US9763952, Example F7) Show SMILES COc1ncc(cc1C(F)F)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)C3CCS(=O)(=O)CC3)cc12 |r| Show InChI InChI=1S/C24H28F2N4O6S/c1-34-23-18(22(25)26)10-16(12-28-23)30-6-7-35-20-13-27-21(11-19(20)30)36-17-2-5-29(14-17)24(31)15-3-8-37(32,33)9-4-15/h10-13,15,17,22H,2-9,14H2,1H3/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204092 (US9539260, F9 | US9763952, Example F9) Show SMILES COCC(=O)N1CC[C@@H](C1)Oc1cc2N(CCOc2cn1)c1cnc(OC)c(c1)C(F)F |r| Show InChI InChI=1S/C21H24F2N4O5/c1-29-12-19(28)26-4-3-14(11-26)32-18-8-16-17(10-24-18)31-6-5-27(16)13-7-15(20(22)23)21(30-2)25-9-13/h7-10,14,20H,3-6,11-12H2,1-2H3/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204093 (US9539260, F10 | US9763952, Example F10) Show SMILES COc1ncc(cc1C(F)F)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)c3cn(C)cn3)cc12 |r| Show InChI InChI=1S/C23H24F2N6O4/c1-29-12-17(28-13-29)23(32)30-4-3-15(11-30)35-20-8-18-19(10-26-20)34-6-5-31(18)14-7-16(21(24)25)22(33-2)27-9-14/h7-10,12-13,15,21H,3-6,11H2,1-2H3/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204095 (US9539260, F12 | US9763952, Example F12) Show SMILES COc1ncc(cc1C)N1CCOc2cnc(OC3CCN(C3)C(=O)C3CCS(=O)(=O)CC3)cc12 Show InChI InChI=1S/C24H30N4O6S/c1-16-11-18(13-26-23(16)32-2)28-7-8-33-21-14-25-22(12-20(21)28)34-19-3-6-27(15-19)24(29)17-4-9-35(30,31)10-5-17/h11-14,17,19H,3-10,15H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM202490 (US9539260, A3 | US9763952, Example A3) Show SMILES O=C(C1CCOCC1)N1CC[C@@H](C1)Oc1ccc2OCCN(c3cncc(c3)S(=O)(=O)N3CCOCC3)c2c1 |r| Show InChI InChI=1S/C27H34N4O7S/c32-27(20-4-10-35-11-5-20)29-6-3-23(19-29)38-22-1-2-26-25(16-22)31(9-14-37-26)21-15-24(18-28-17-21)39(33,34)30-7-12-36-13-8-30/h1-2,15-18,20,23H,3-14,19H2/t23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM202513 (US9539260, A12 | US9763952, Example A12) Show SMILES CCC(=O)N1CC[C@@H](C1)Oc1ccc2OCCN(c3cnc(OC)c(Cl)c3)c2c1 |r| Show InChI InChI=1S/C21H24ClN3O4/c1-3-20(26)24-7-6-16(13-24)29-15-4-5-19-18(11-15)25(8-9-28-19)14-10-17(22)21(27-2)23-12-14/h4-5,10-12,16H,3,6-9,13H2,1-2H3/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204120 (US9539260, K | US9763952, Example K) Show SMILES COc1ncc(cc1C#N)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)[C@@H]3CCN(C3)C(C)=O)cc12 |r| Show InChI InChI=1S/C26H29N5O5/c1-17(32)29-7-5-18(15-29)26(33)30-8-6-22(16-30)36-21-3-4-24-23(12-21)31(9-10-35-24)20-11-19(13-27)25(34-2)28-14-20/h3-4,11-12,14,18,22H,5-10,15-16H2,1-2H3/t18-,22+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM203908 (US9539260, C24 | US9539260, C25 | US9763952, Examp...) Show SMILES COc1ncc(cc1C#N)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)C3COCCO3)cc12 |r,w:24.27| Show InChI InChI=1S/C24H26N4O6/c1-30-23-16(12-25)10-17(13-26-23)28-6-7-32-21-3-2-18(11-20(21)28)34-19-4-5-27(14-19)24(29)22-15-31-8-9-33-22/h2-3,10-11,13,19,22H,4-9,14-15H2,1H3/t19-,22?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204008 (US9539260, D12 | US9763952, Example D12) Show SMILES COCC(=O)N1CC[C@@H](C1)Oc1ccc2OCCN(c3cnc(OC)c(c3)C#N)c2c1 |r| Show InChI InChI=1S/C22H24N4O5/c1-28-14-21(27)25-6-5-18(13-25)31-17-3-4-20-19(10-17)26(7-8-30-20)16-9-15(11-23)22(29-2)24-12-16/h3-4,9-10,12,18H,5-8,13-14H2,1-2H3/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204062 (US9539260, D28 | US9539260, D29 | US9763952, Examp...) Show SMILES COc1ncc(cc1C#N)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)C3CCOC3)cc12 |r| Show InChI InChI=1S/C24H26N4O5/c1-30-23-17(12-25)10-18(13-26-23)28-7-9-32-22-3-2-19(11-21(22)28)33-20-4-6-27(14-20)24(29)16-5-8-31-15-16/h2-3,10-11,13,16,20H,4-9,14-15H2,1H3/t16?,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204070 (US9539260, D35 | US9539260, D36 | US9763952, Examp...) Show SMILES COC1CCC(CC1)C(=O)N1CC[C@@H](C1)Oc1ccc2OCCN(c3cnc(OC)c(c3)C#N)c2c1 |r,wD:13.16,(8.9,-5.23,;8.51,-3.74,;7.02,-3.35,;5.93,-4.43,;4.44,-4.04,;4.04,-2.55,;5.13,-1.46,;6.62,-1.86,;2.56,-2.15,;2.16,-.66,;1.47,-3.24,;.56,-4.48,;-.9,-4.01,;-.9,-2.47,;.56,-1.99,;-2.24,-1.7,;-3.57,-2.47,;-3.57,-4.01,;-4.9,-4.78,;-6.24,-4.01,;-7.57,-4.78,;-8.9,-4.01,;-8.9,-2.47,;-7.57,-1.7,;-7.57,-.16,;-8.9,.61,;-8.9,2.15,;-7.57,2.92,;-7.57,4.46,;-6.24,5.23,;-6.24,2.15,;-6.24,.61,;-4.9,2.92,;-3.57,3.69,;-6.24,-2.47,;-4.9,-1.7,)| Show InChI InChI=1S/C27H32N4O5/c1-33-21-5-3-18(4-6-21)27(32)30-10-9-23(17-30)36-22-7-8-25-24(14-22)31(11-12-35-25)20-13-19(15-28)26(34-2)29-16-20/h7-8,13-14,16,18,21,23H,3-6,9-12,17H2,1-2H3/t18?,21?,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204077 (US9539260, E3 | US9763952, Example E3) Show SMILES COc1ncc(cc1C)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)C3CCOCC3)cc12 |r| Show InChI InChI=1S/C24H30N4O5/c1-16-11-18(13-26-23(16)30-2)28-7-10-32-21-14-25-22(12-20(21)28)33-19-3-6-27(15-19)24(29)17-4-8-31-9-5-17/h11-14,17,19H,3-10,15H2,1-2H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204083 (US9539260, E11 | US9763952, Example E11) Show SMILES Cc1cc(cnc1OC(F)F)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)C3CC3)cc12 |r| Show InChI InChI=1S/C22H24F2N4O4/c1-13-8-15(10-26-20(13)32-22(23)24)28-6-7-30-18-11-25-19(9-17(18)28)31-16-4-5-27(12-16)21(29)14-2-3-14/h8-11,14,16,22H,2-7,12H2,1H3/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM203414 (US9539260, B70 | US9763952, Example B70) Show SMILES CS(=O)(=O)c1ncc(cc1C(F)F)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)C3CCOCC3)cc12 |r| Show InChI InChI=1S/C25H29F2N3O6S/c1-37(32,33)24-20(23(26)27)12-17(14-28-24)30-8-11-35-22-3-2-18(13-21(22)30)36-19-4-7-29(15-19)25(31)16-5-9-34-10-6-16/h2-3,12-14,16,19,23H,4-11,15H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM203425 (US9539260, B79 | US9763952, Example B79) Show SMILES CS(=O)(=O)c1ncc(cc1Cl)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)C3CCOCC3)cc12 |r| Show InChI InChI=1S/C24H28ClN3O6S/c1-35(30,31)23-20(25)12-17(14-26-23)28-8-11-33-22-3-2-18(13-21(22)28)34-19-4-7-27(15-19)24(29)16-5-9-32-10-6-16/h2-3,12-14,16,19H,4-11,15H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM203661 (US9539260, B108 | US9763952, Example B108) Show SMILES COc1ncc(cc1Cl)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)c3cnco3)cc12 |r| Show InChI InChI=1S/C22H21ClN4O5/c1-29-21-17(23)8-14(10-25-21)27-6-7-30-19-3-2-15(9-18(19)27)32-16-4-5-26(12-16)22(28)20-11-24-13-31-20/h2-3,8-11,13,16H,4-7,12H2,1H3/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM203662 (US9539260, B109 | US9763952, Example B109) Show SMILES COc1ncc(cc1Cl)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)CC#N)cc12 |r| Show InChI InChI=1S/C21H21ClN4O4/c1-28-21-17(22)10-14(12-24-21)26-8-9-29-19-3-2-15(11-18(19)26)30-16-5-7-25(13-16)20(27)4-6-23/h2-3,10-12,16H,4-5,7-9,13H2,1H3/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM203663 (US9539260, B110 | US9763952, Example B110) Show SMILES COc1ncc(cc1Cl)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)CS(C)(=O)=O)cc12 |r| Show InChI InChI=1S/C21H24ClN3O6S/c1-29-21-17(22)9-14(11-23-21)25-7-8-30-19-4-3-15(10-18(19)25)31-16-5-6-24(12-16)20(26)13-32(2,27)28/h3-4,9-11,16H,5-8,12-13H2,1-2H3/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM203396 (US9539260, B52 | US9539260, B53 | US9763952, Examp...) Show SMILES Cc1cc(cnc1S(C)(=O)=O)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)C3CCOC3)cc12 |r,w:25.28| Show InChI InChI=1S/C24H29N3O6S/c1-16-11-18(13-25-23(16)34(2,29)30)27-8-10-32-22-4-3-19(12-21(22)27)33-20-5-7-26(14-20)24(28)17-6-9-31-15-17/h3-4,11-13,17,20H,5-10,14-15H2,1-2H3/t17?,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204102 (US9539260, H3 | US9539260, H4 | US9763952, Example...) Show SMILES Cc1cc(cnc1S(C)(=O)=O)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)C3COCCO3)cc12 |r,w:25.28| Show InChI InChI=1S/C24H29N3O7S/c1-16-11-17(13-25-23(16)35(2,29)30)27-7-8-32-21-4-3-18(12-20(21)27)34-19-5-6-26(14-19)24(28)22-15-31-9-10-33-22/h3-4,11-13,19,22H,5-10,14-15H2,1-2H3/t19-,22?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM203381 (US9539260, B38 | US9763952, Example B38) Show SMILES COc1cc(cnc1OC)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)C3CCOCC3)cc12 |r| Show InChI InChI=1S/C25H31N3O6/c1-30-23-13-18(15-26-24(23)31-2)28-9-12-33-22-4-3-19(14-21(22)28)34-20-5-8-27(16-20)25(29)17-6-10-32-11-7-17/h3-4,13-15,17,20H,5-12,16H2,1-2H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM203396 (US9539260, B52 | US9539260, B53 | US9763952, Examp...) Show SMILES Cc1cc(cnc1S(C)(=O)=O)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)C3CCOC3)cc12 |r,w:25.28| Show InChI InChI=1S/C24H29N3O6S/c1-16-11-18(13-25-23(16)34(2,29)30)27-8-10-32-22-4-3-19(12-21(22)27)33-20-5-7-26(14-20)24(28)17-6-9-31-15-17/h3-4,11-13,17,20H,5-10,14-15H2,1-2H3/t17?,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent									US Patent US9763952 (2017) BindingDB Entry DOI: 10.7270/Q2V40X9Z
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204083 (US9539260, E11 | US9763952, Example E11) Show SMILES Cc1cc(cnc1OC(F)F)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)C3CC3)cc12 |r| Show InChI InChI=1S/C22H24F2N4O4/c1-13-8-15(10-26-20(13)32-22(23)24)28-6-7-30-18-11-25-19(9-17(18)28)31-16-4-5-27(12-16)21(29)14-2-3-14/h8-11,14,16,22H,2-7,12H2,1H3/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...				US Patent US9539260 (2017) BindingDB Entry DOI: 10.7270/Q2W37TH1
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204084 (US9539260, F1) Show SMILES COc1ncc(cc1C)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)C3CCS(=O)(=O)CC3)cc12 |r| Show InChI InChI=1S/C24H30N4O6S/c1-16-11-18(13-26-23(16)32-2)28-7-8-33-21-14-25-22(12-20(21)28)34-19-3-6-27(15-19)24(29)17-4-9-35(30,31)10-5-17/h11-14,17,19H,3-10,15H2,1-2H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...				US Patent US9539260 (2017) BindingDB Entry DOI: 10.7270/Q2W37TH1
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204087 (US9539260, F4 | US9763952, Example F4) Show SMILES COc1ncc(cc1C#N)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)C3CCOCC3)cc12 |r| Show InChI InChI=1S/C24H27N5O5/c1-31-23-17(12-25)10-18(13-27-23)29-6-9-33-21-14-26-22(11-20(21)29)34-19-2-5-28(15-19)24(30)16-3-7-32-8-4-16/h10-11,13-14,16,19H,2-9,15H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...				US Patent US9539260 (2017) BindingDB Entry DOI: 10.7270/Q2W37TH1
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204089 (US9539260, F6 | US9763952, Example F6) Show SMILES Cc1cc(cnc1S(C)(=O)=O)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)C3CCOCC3)cc12 |r| Show InChI InChI=1S/C24H30N4O6S/c1-16-11-18(13-26-23(16)35(2,30)31)28-7-10-33-21-14-25-22(12-20(21)28)34-19-3-6-27(15-19)24(29)17-4-8-32-9-5-17/h11-14,17,19H,3-10,15H2,1-2H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...				US Patent US9539260 (2017) BindingDB Entry DOI: 10.7270/Q2W37TH1
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204090 (US9539260, F7 | US9763952, Example F7) Show SMILES COc1ncc(cc1C(F)F)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)C3CCS(=O)(=O)CC3)cc12 |r| Show InChI InChI=1S/C24H28F2N4O6S/c1-34-23-18(22(25)26)10-16(12-28-23)30-6-7-35-20-13-27-21(11-19(20)30)36-17-2-5-29(14-17)24(31)15-3-8-37(32,33)9-4-15/h10-13,15,17,22H,2-9,14H2,1H3/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...				US Patent US9539260 (2017) BindingDB Entry DOI: 10.7270/Q2W37TH1
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204092 (US9539260, F9 | US9763952, Example F9) Show SMILES COCC(=O)N1CC[C@@H](C1)Oc1cc2N(CCOc2cn1)c1cnc(OC)c(c1)C(F)F |r| Show InChI InChI=1S/C21H24F2N4O5/c1-29-12-19(28)26-4-3-14(11-26)32-18-8-16-17(10-24-18)31-6-5-27(16)13-7-15(20(22)23)21(30-2)25-9-13/h7-10,14,20H,3-6,11-12H2,1-2H3/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...				US Patent US9539260 (2017) BindingDB Entry DOI: 10.7270/Q2W37TH1
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204093 (US9539260, F10 | US9763952, Example F10) Show SMILES COc1ncc(cc1C(F)F)N1CCOc2cnc(O[C@H]3CCN(C3)C(=O)c3cn(C)cn3)cc12 |r| Show InChI InChI=1S/C23H24F2N6O4/c1-29-12-17(28-13-29)23(32)30-4-3-15(11-30)35-20-8-18-19(10-26-20)34-6-5-31(18)14-7-16(21(24)25)22(33-2)27-9-14/h7-10,12-13,15,21H,3-6,11H2,1-2H3/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...				US Patent US9539260 (2017) BindingDB Entry DOI: 10.7270/Q2W37TH1
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM204095 (US9539260, F12 | US9763952, Example F12) Show SMILES COc1ncc(cc1C)N1CCOc2cnc(OC3CCN(C3)C(=O)C3CCS(=O)(=O)CC3)cc12 Show InChI InChI=1S/C24H30N4O6S/c1-16-11-18(13-26-23(16)32-2)28-7-8-33-21-14-25-22(12-20(21)28)34-19-3-6-27(15-19)24(29)17-4-9-35(30,31)10-5-17/h11-14,17,19H,3-10,15H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...				US Patent US9539260 (2017) BindingDB Entry DOI: 10.7270/Q2W37TH1
					More data for this Ligand-Target Pair

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