| Reaction Details |
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 | Report a problem with these data |
| Target | Advanced glycosylation end product-specific receptor |
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| Ligand | BDBM453295 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | High-Throughput Screening Assay |
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| Kd | 10000±n/a nM |
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| Citation |  Schmidt, AM; Ramasamy, R; Shekhtman, A; Rai, V; Manigrasso, MB Amino, amido and heterocyclic compounds as modulators of RAGE activity and uses thereof US Patent US10729695 Publication Date 8/4/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Advanced glycosylation end product-specific receptor |
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| Name: | Advanced glycosylation end product-specific receptor |
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| Synonyms: | AGER | RAGE | RAGE_HUMAN | Receptor for advanced glycosylation end products |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42800.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1339877 |
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| Residue: | 404 |
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| Sequence: | MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA
WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI
PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH
PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL
VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS
CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV
ILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP
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| BDBM453295 |
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| n/a |
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| Name | BDBM453295 |
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| Synonyms: | US10729695, Compound CD-7 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21N3O |
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| Mol. Mass. | 295.3788 |
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| SMILES | CN(CC(O)Cn1cnc2ccccc12)Cc1ccccc1 |
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| Structure | 
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