Compile Data Set for Download or QSAR

Found 229 hits with Last Name = 'schmidt' and Initial = 'am'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308196 (2-(3-Chloro-4-hydroxyanilino)-9-methoxy-5,7-dihydr...) Show SMILES COc1ccc-2c(NC(=O)Cc3cnc(Nc4ccc(O)c(Cl)c4)nc-23)c1 Show InChI InChI=1S/C19H15ClN4O3/c1-27-12-3-4-13-15(8-12)23-17(26)6-10-9-21-19(24-18(10)13)22-11-2-5-16(25)14(20)7-11/h2-5,7-9,25H,6H2,1H3,(H,23,26)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308194 (2-(3-Hydroxyanilino)-9-methoxy-5,7-dihydro-6H-pyri...) Show SMILES COc1ccc-2c(NC(=O)Cc3cnc(Nc4cccc(O)c4)nc-23)c1 Show InChI InChI=1S/C19H16N4O3/c1-26-14-5-6-15-16(9-14)22-17(25)7-11-10-20-19(23-18(11)15)21-12-3-2-4-13(24)8-12/h2-6,8-10,24H,7H2,1H3,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308195 (2-(3-Hydroxy-4-methoxyanilino)-9-methoxy-5,7-dihyd...) Show SMILES COc1ccc-2c(NC(=O)Cc3cnc(Nc4ccc(OC)c(O)c4)nc-23)c1 Show InChI InChI=1S/C20H18N4O4/c1-27-13-4-5-14-15(9-13)23-18(26)7-11-10-21-20(24-19(11)14)22-12-3-6-17(28-2)16(25)8-12/h3-6,8-10,25H,7H2,1-2H3,(H,23,26)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308191 (2-(4-Hydroxyanilino)-9-methoxy-5,7-dihydro-6H-pyri...) Show SMILES COc1ccc-2c(NC(=O)Cc3cnc(Nc4ccc(O)cc4)nc-23)c1 Show InChI InChI=1S/C19H16N4O3/c1-26-14-6-7-15-16(9-14)22-17(25)8-11-10-20-19(23-18(11)15)21-12-2-4-13(24)5-3-12/h2-7,9-10,24H,8H2,1H3,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308189 (2-(3-Chloro-4-hydroxyanilino)-5,7-dihydro-6H-pyrim...) Show SMILES Oc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1Cl Show InChI InChI=1S/C18H13ClN4O2/c19-13-8-11(5-6-15(13)24)21-18-20-9-10-7-16(25)22-14-4-2-1-3-12(14)17(10)23-18/h1-6,8-9,24H,7H2,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308192 (2-(4-Methoxyanilino)-9-methoxy-5,7-dihydro-6H-pyri...) Show SMILES COc1ccc(Nc2ncc3CC(=O)Nc4cc(OC)ccc4-c3n2)cc1 Show InChI InChI=1S/C20H18N4O3/c1-26-14-5-3-13(4-6-14)22-20-21-11-12-9-18(25)23-17-10-15(27-2)7-8-16(17)19(12)24-20/h3-8,10-11H,9H2,1-2H3,(H,23,25)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308184 (2-(3-Hydroxyanilino)-5,7-dihydro-6H-pyrimido[5,4-d...) Show SMILES Oc1cccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)c1 Show InChI InChI=1S/C18H14N4O2/c23-13-5-3-4-12(9-13)20-18-19-10-11-8-16(24)21-15-7-2-1-6-14(15)17(11)22-18/h1-7,9-10,23H,8H2,(H,21,24)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308193 (2-(4-Ethoxyanilino)-9-methoxy-5,7-dihydro-6H-pyrim...) Show SMILES CCOc1ccc(Nc2ncc3CC(=O)Nc4cc(OC)ccc4-c3n2)cc1 Show InChI InChI=1S/C21H20N4O3/c1-3-28-15-6-4-14(5-7-15)23-21-22-12-13-10-19(26)24-18-11-16(27-2)8-9-17(18)20(13)25-21/h4-9,11-12H,3,10H2,1-2H3,(H,24,26)(H,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) Show SMILES CN[C@@H]1CC2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in HUE cells assessed as inhibition of VEGF-induced autophosphorylation treated for 90 mins before VEGF challenge by ELISA				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308188 (2-(3-Hydroxy-4-methoxyanilino)-5,7-dihydro-6H-pyri...) Show SMILES COc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1O Show InChI InChI=1S/C19H16N4O3/c1-26-16-7-6-12(9-15(16)24)21-19-20-10-11-8-17(25)22-14-5-3-2-4-13(14)18(11)23-19/h2-7,9-10,24H,8H2,1H3,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308231 (2-(4-Hydroxyanilino)-5,7-dihydro-6H-pyrimido[5,4-d...) Show SMILES Oc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1 Show InChI InChI=1S/C18H14N4O2/c23-13-7-5-12(6-8-13)20-18-19-10-11-9-16(24)21-15-4-2-1-3-14(15)17(11)22-18/h1-8,10,23H,9H2,(H,21,24)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308201 (2-(3-Chloro-4-hydroxyanilino)-5,7-dihydro-6H-pyrid...) Show SMILES Oc1ccc(Nc2ncc3CC(=O)Nc4ccncc4-c3n2)cc1Cl Show InChI InChI=1S/C17H12ClN5O2/c18-12-6-10(1-2-14(12)24)21-17-20-7-9-5-15(25)22-13-3-4-19-8-11(13)16(9)23-17/h1-4,6-8,24H,5H2,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308227 (2-(4-Methoxyanilino)-5,7-dihydro-6H-pyrimido[5,4-d...) Show SMILES COc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1 Show InChI InChI=1S/C19H16N4O2/c1-25-14-8-6-13(7-9-14)21-19-20-11-12-10-17(24)22-16-5-3-2-4-15(16)18(12)23-19/h2-9,11H,10H2,1H3,(H,22,24)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308199 (2-(4-Ethoxyanilino)-5,7-dihydro-6H-pyrido[4,3-b]py...) Show SMILES CCOc1ccc(Nc2ncc3CC(=O)Nc4ccncc4-c3n2)cc1 Show InChI InChI=1S/C19H17N5O2/c1-2-26-14-5-3-13(4-6-14)22-19-21-10-12-9-17(25)23-16-7-8-20-11-15(16)18(12)24-19/h3-8,10-11H,2,9H2,1H3,(H,23,25)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308224 (2-(4-Ethoxyanilino)-5,7-dihydro-6H-pyrimido[5,4-d]...) Show SMILES CCOc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1 Show InChI InChI=1S/C20H18N4O2/c1-2-26-15-9-7-14(8-10-15)22-20-21-12-13-11-18(25)23-17-6-4-3-5-16(17)19(13)24-20/h3-10,12H,2,11H2,1H3,(H,23,25)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308197 (2-(4-Hydroxyanilino)-5,7-dihydro-6H-pyrido[4,3-b]p...) Show SMILES Oc1ccc(Nc2ncc3CC(=O)Nc4ccncc4-c3n2)cc1 Show InChI InChI=1S/C17H13N5O2/c23-12-3-1-11(2-4-12)20-17-19-8-10-7-15(24)21-14-5-6-18-9-13(14)16(10)22-17/h1-6,8-9,23H,7H2,(H,21,24)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308200 (2-(3-Hydroxyanilino)-5,7-dihydro-6H-pyrido[4,3-b]p...) Show SMILES Oc1cccc(Nc2ncc3CC(=O)Nc4ccncc4-c3n2)c1 Show InChI InChI=1S/C17H13N5O2/c23-12-3-1-2-11(7-12)20-17-19-8-10-6-15(24)21-14-4-5-18-9-13(14)16(10)22-17/h1-5,7-9,23H,6H2,(H,21,24)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308225 (2-Anilino-5,7-dihydro-6H-pyrimido[5,4-d][1]benzaze...) Show SMILES O=C1Cc2cnc(Nc3ccccc3)nc2-c2ccccc2N1 Show InChI InChI=1S/C18H14N4O/c23-16-10-12-11-19-18(20-13-6-2-1-3-7-13)22-17(12)14-8-4-5-9-15(14)21-16/h1-9,11H,10H2,(H,21,23)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308195 (2-(3-Hydroxy-4-methoxyanilino)-9-methoxy-5,7-dihyd...) Show SMILES COc1ccc-2c(NC(=O)Cc3cnc(Nc4ccc(OC)c(O)c4)nc-23)c1 Show InChI InChI=1S/C20H18N4O4/c1-27-13-4-5-14-15(9-13)23-18(26)7-11-10-21-20(24-19(11)14)22-12-3-6-17(28-2)16(25)8-12/h3-6,8-10,25H,7H2,1-2H3,(H,23,26)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308198 (2-(4-Methoxyanilino)-5,7-dihydro-6H-pyrido[4,3-b]p...) Show SMILES COc1ccc(Nc2ncc3CC(=O)Nc4ccncc4-c3n2)cc1 Show InChI InChI=1S/C18H15N5O2/c1-25-13-4-2-12(3-5-13)21-18-20-9-11-8-16(24)22-15-6-7-19-10-14(15)17(11)23-18/h2-7,9-10H,8H2,1H3,(H,22,24)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308230 (2-(4-Methylanilino)-5,7-dihydro-6H-pyrimido[5,4-d]...) Show SMILES Cc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1 Show InChI InChI=1S/C19H16N4O/c1-12-6-8-14(9-7-12)21-19-20-11-13-10-17(24)22-16-5-3-2-4-15(16)18(13)23-19/h2-9,11H,10H2,1H3,(H,22,24)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308228 (2-(4-Chloroanilino)-5,7-dihydro-6H-pyrimido[5,4-d]...) Show SMILES Clc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1 Show InChI InChI=1S/C18H13ClN4O/c19-12-5-7-13(8-6-12)21-18-20-10-11-9-16(24)22-15-4-2-1-3-14(15)17(11)23-18/h1-8,10H,9H2,(H,22,24)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308232 (2-(4-Bromoanilino)-5,7-dihydro-6H-pyrimido[5,4-d][...) Show SMILES Brc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1 Show InChI InChI=1S/C18H13BrN4O/c19-12-5-7-13(8-6-12)21-18-20-10-11-9-16(24)22-15-4-2-1-3-14(15)17(11)23-18/h1-8,10H,9H2,(H,22,24)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308193 (2-(4-Ethoxyanilino)-9-methoxy-5,7-dihydro-6H-pyrim...) Show SMILES CCOc1ccc(Nc2ncc3CC(=O)Nc4cc(OC)ccc4-c3n2)cc1 Show InChI InChI=1S/C21H20N4O3/c1-3-28-15-6-4-14(5-7-15)23-21-22-12-13-10-19(26)24-18-11-16(27-2)8-9-17(18)20(13)25-21/h4-9,11-12H,3,10H2,1-2H3,(H,24,26)(H,22,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in HUE cells assessed as inhibition of VEGF-induced autophosphorylation treated for 90 mins before VEGF challenge by ELISA				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308229 (2-(4-Nitroanilino)-5,7-dihydro-6H-pyrimido[5,4-d][...) Show SMILES [O-][N+](=O)c1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1 Show InChI InChI=1S/C18H13N5O3/c24-16-9-11-10-19-18(20-12-5-7-13(8-6-12)23(25)26)22-17(11)14-3-1-2-4-15(14)21-16/h1-8,10H,9H2,(H,21,24)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308192 (2-(4-Methoxyanilino)-9-methoxy-5,7-dihydro-6H-pyri...) Show SMILES COc1ccc(Nc2ncc3CC(=O)Nc4cc(OC)ccc4-c3n2)cc1 Show InChI InChI=1S/C20H18N4O3/c1-26-14-5-3-13(4-6-14)22-20-21-11-12-9-18(25)23-17-10-15(27-2)7-8-16(17)19(12)24-20/h3-8,10-11H,9H2,1-2H3,(H,23,25)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308196 (2-(3-Chloro-4-hydroxyanilino)-9-methoxy-5,7-dihydr...) Show SMILES COc1ccc-2c(NC(=O)Cc3cnc(Nc4ccc(O)c(Cl)c4)nc-23)c1 Show InChI InChI=1S/C19H15ClN4O3/c1-27-12-3-4-13-15(8-12)23-17(26)6-10-9-21-19(24-18(10)13)22-11-2-5-16(25)14(20)7-11/h2-5,7-9,25H,6H2,1H3,(H,23,26)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308226 (2-(4-Iodoanilino)-5,7-dihydro-6H-pyrimido[5,4-d][1...) Show SMILES Ic1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1 Show InChI InChI=1S/C18H13IN4O/c19-12-5-7-13(8-6-12)21-18-20-10-11-9-16(24)22-15-4-2-1-3-14(15)17(11)23-18/h1-8,10H,9H2,(H,22,24)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308196 (2-(3-Chloro-4-hydroxyanilino)-9-methoxy-5,7-dihydr...) Show SMILES COc1ccc-2c(NC(=O)Cc3cnc(Nc4ccc(O)c(Cl)c4)nc-23)c1 Show InChI InChI=1S/C19H15ClN4O3/c1-27-12-3-4-13-15(8-12)23-17(26)6-10-9-21-19(24-18(10)13)22-11-2-5-16(25)14(20)7-11/h2-5,7-9,25H,6H2,1H3,(H,23,26)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in HUE cells assessed as inhibition of VEGF-induced autophosphorylation treated for 90 mins before VEGF challenge by ELISA				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308187 (2-(2-Hydroxyanilino)-5,7-dihydro-6H-pyrimido[5,4-d...) Show SMILES Oc1ccccc1Nc1ncc2CC(=O)Nc3ccccc3-c2n1 Show InChI InChI=1S/C18H14N4O2/c23-15-8-4-3-7-14(15)21-18-19-10-11-9-16(24)20-13-6-2-1-5-12(13)17(11)22-18/h1-8,10,23H,9H2,(H,20,24)(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308208 (2-Phenyl-6,8-dihydro-7H-pyrazolo[5',1':2,3]pyrimid...) Show SMILES O=C1Cc2cnc3cc(nn3c2-c2ccccc2N1)-c1ccccc1 Show InChI InChI=1S/C20H14N4O/c25-19-10-14-12-21-18-11-17(13-6-2-1-3-7-13)23-24(18)20(14)15-8-4-5-9-16(15)22-19/h1-9,11-12H,10H2,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308206 (2-(3-Chloro-4-hydroxyanilino)-5,7-dihydro-6H-pyrid...) Show SMILES Oc1ccc(Nc2ncc3CC(=O)Nc4cccnc4-c3n2)cc1Cl Show InChI InChI=1S/C17H12ClN5O2/c18-11-7-10(3-4-13(11)24)21-17-20-8-9-6-14(25)22-12-2-1-5-19-16(12)15(9)23-17/h1-5,7-8,24H,6H2,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308191 (2-(4-Hydroxyanilino)-9-methoxy-5,7-dihydro-6H-pyri...) Show SMILES COc1ccc-2c(NC(=O)Cc3cnc(Nc4ccc(O)cc4)nc-23)c1 Show InChI InChI=1S/C19H16N4O3/c1-26-14-6-7-15-16(9-14)22-17(25)8-11-10-20-19(23-18(11)15)21-12-2-4-13(24)5-3-12/h2-7,9-10,24H,8H2,1H3,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308194 (2-(3-Hydroxyanilino)-9-methoxy-5,7-dihydro-6H-pyri...) Show SMILES COc1ccc-2c(NC(=O)Cc3cnc(Nc4cccc(O)c4)nc-23)c1 Show InChI InChI=1S/C19H16N4O3/c1-26-14-5-6-15-16(9-14)22-17(25)7-11-10-20-19(23-18(11)15)21-12-3-2-4-13(24)8-12/h2-6,8-10,24H,7H2,1H3,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308190 (2-(4-Hydroxy-2-methylanilino)-5,7-dihydro-6H-pyrim...) Show SMILES Cc1cc(O)ccc1Nc1ncc2CC(=O)Nc3ccccc3-c2n1 Show InChI InChI=1S/C19H16N4O2/c1-11-8-13(24)6-7-15(11)22-19-20-10-12-9-17(25)21-16-5-3-2-4-14(16)18(12)23-19/h2-8,10,24H,9H2,1H3,(H,21,25)(H,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308201 (2-(3-Chloro-4-hydroxyanilino)-5,7-dihydro-6H-pyrid...) Show SMILES Oc1ccc(Nc2ncc3CC(=O)Nc4ccncc4-c3n2)cc1Cl Show InChI InChI=1S/C17H12ClN5O2/c18-12-6-10(1-2-14(12)24)21-17-20-7-9-5-15(25)22-13-3-4-19-8-11(13)16(9)23-17/h1-4,6-8,24H,5H2,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308203 (2-(4-Methoxyanilino)-5,7-dihydro-6H-pyrido[3,2-b]p...) Show SMILES COc1ccc(Nc2ncc3CC(=O)Nc4cccnc4-c3n2)cc1 Show InChI InChI=1S/C18H15N5O2/c1-25-13-6-4-12(5-7-13)21-18-20-10-11-9-15(24)22-14-3-2-8-19-17(14)16(11)23-18/h2-8,10H,9H2,1H3,(H,22,24)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308184 (2-(3-Hydroxyanilino)-5,7-dihydro-6H-pyrimido[5,4-d...) Show SMILES Oc1cccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)c1 Show InChI InChI=1S/C18H14N4O2/c23-13-5-3-4-12(9-13)20-18-19-10-11-8-16(24)21-15-7-2-1-6-14(15)17(11)22-18/h1-7,9-10,23H,8H2,(H,21,24)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in HUE cells assessed as inhibition of VEGF-induced autophosphorylation treated for 90 mins before VEGF challenge by ELISA				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308199 (2-(4-Ethoxyanilino)-5,7-dihydro-6H-pyrido[4,3-b]py...) Show SMILES CCOc1ccc(Nc2ncc3CC(=O)Nc4ccncc4-c3n2)cc1 Show InChI InChI=1S/C19H17N5O2/c1-2-26-14-5-3-13(4-6-14)22-19-21-10-12-9-17(25)23-16-7-8-20-11-15(16)18(12)24-19/h3-8,10-11H,2,9H2,1H3,(H,23,25)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308210 (10-Methoxy-2-phenyl-6,8-dihydro-7H-pyrazolo[5',1':...) Show SMILES COc1ccc-2c(NC(=O)Cc3cnc4cc(nn4c-23)-c2ccccc2)c1 Show InChI InChI=1S/C21H16N4O2/c1-27-15-7-8-16-18(10-15)23-20(26)9-14-12-22-19-11-17(24-25(19)21(14)16)13-5-3-2-4-6-13/h2-8,10-12H,9H2,1H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308211 (2-Phenyl-6,8-dihydro-7H-pyrazolo[5',1':2,3]pyrimid...) Show SMILES O=C1Cc2cnc3cc(nn3c2-c2cnccc2N1)-c1ccccc1 Show InChI InChI=1S/C19H13N5O/c25-18-8-13-10-21-17-9-16(12-4-2-1-3-5-12)23-24(17)19(13)14-11-20-7-6-15(14)22-18/h1-7,9-11H,8H2,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308204 (2-(4-Ethoxyanilino)-5,7-dihydro-6H-pyrido[3,2-b]py...) Show SMILES CCOc1ccc(Nc2ncc3CC(=O)Nc4cccnc4-c3n2)cc1 Show InChI InChI=1S/C19H17N5O2/c1-2-26-14-7-5-13(6-8-14)22-19-21-11-12-10-16(25)23-15-4-3-9-20-18(15)17(12)24-19/h3-9,11H,2,10H2,1H3,(H,23,25)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308200 (2-(3-Hydroxyanilino)-5,7-dihydro-6H-pyrido[4,3-b]p...) Show SMILES Oc1cccc(Nc2ncc3CC(=O)Nc4ccncc4-c3n2)c1 Show InChI InChI=1S/C17H13N5O2/c23-12-3-1-2-11(7-12)20-17-19-8-10-6-15(24)21-14-4-5-18-9-13(14)16(10)22-17/h1-5,7-9,23H,6H2,(H,21,24)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308188 (2-(3-Hydroxy-4-methoxyanilino)-5,7-dihydro-6H-pyri...) Show SMILES COc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1O Show InChI InChI=1S/C19H16N4O3/c1-26-16-7-6-12(9-15(16)24)21-19-20-10-11-8-17(25)22-14-5-3-2-4-13(14)18(11)23-19/h2-7,9-10,24H,8H2,1H3,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in HUE cells assessed as inhibition of VEGF-induced autophosphorylation treated for 90 mins before VEGF challenge by ELISA				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308198 (2-(4-Methoxyanilino)-5,7-dihydro-6H-pyrido[4,3-b]p...) Show SMILES COc1ccc(Nc2ncc3CC(=O)Nc4ccncc4-c3n2)cc1 Show InChI InChI=1S/C18H15N5O2/c1-25-13-4-2-12(3-5-13)21-18-20-9-11-8-16(24)22-15-6-7-19-10-14(15)17(11)23-18/h2-7,9-10H,8H2,1H3,(H,22,24)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308197 (2-(4-Hydroxyanilino)-5,7-dihydro-6H-pyrido[4,3-b]p...) Show SMILES Oc1ccc(Nc2ncc3CC(=O)Nc4ccncc4-c3n2)cc1 Show InChI InChI=1S/C17H13N5O2/c23-12-3-1-11(2-4-12)20-17-19-8-10-7-15(24)21-14-5-6-18-9-13(14)16(10)22-17/h1-6,8-9,23H,7H2,(H,21,24)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308205 (2-(3-Hydroxyanilino)-5,7-dihydro-6H-pyrido[3,2-b]p...) Show SMILES Oc1cccc(Nc2ncc3CC(=O)Nc4cccnc4-c3n2)c1 Show InChI InChI=1S/C17H13N5O2/c23-12-4-1-3-11(8-12)20-17-19-9-10-7-14(24)21-13-5-2-6-18-16(13)15(10)22-17/h1-6,8-9,23H,7H2,(H,21,24)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308202 (2-(4-Hydroxyanilino)-5,7-dihydro-6H-pyrido[3,2-b]p...) Show SMILES Oc1ccc(Nc2ncc3CC(=O)Nc4cccnc4-c3n2)cc1 Show InChI InChI=1S/C17H13N5O2/c23-12-5-3-11(4-6-12)20-17-19-9-10-8-14(24)21-13-2-1-7-18-16(13)15(10)22-17/h1-7,9,23H,8H2,(H,21,24)(H,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50308188 (2-(3-Hydroxy-4-methoxyanilino)-5,7-dihydro-6H-pyri...) Show SMILES COc1ccc(Nc2ncc3CC(=O)Nc4ccccc4-c3n2)cc1O Show InChI InChI=1S/C19H16N4O3/c1-26-16-7-6-12(9-15(16)24)21-19-20-10-11-8-17(25)22-14-5-3-2-4-13(14)18(11)23-19/h2-7,9-10,24H,8H2,1H3,(H,22,25)(H,20,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50308185 (2-(2-Chloroanilino)-5,7-dihydro-6H-pyrimido[5,4-d]...) Show SMILES Clc1ccccc1Nc1ncc2CC(=O)Nc3ccccc3-c2n1 Show InChI InChI=1S/C18H13ClN4O/c19-13-6-2-4-8-15(13)22-18-20-10-11-9-16(24)21-14-7-3-1-5-12(14)17(11)23-18/h1-8,10H,9H2,(H,21,24)(H,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Braunschweig Curated by ChEMBL					Assay Description Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATP				J Med Chem 53: 2433-42 (2010) Article DOI: 10.1021/jm901388c BindingDB Entry DOI: 10.7270/Q24J0G22
					More data for this Ligand-Target Pair

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