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TargetAdvanced glycosylation end product-specific receptor
LigandBDBM453304
Substrate/Competitorn/a
Meas. Tech.High-Throughput Screening Assay
Kd 78.0±n/a nM
Citation Schmidt, AMRamasamy, RShekhtman, ARai, VManigrasso, MB Amino, amido and heterocyclic compounds as modulators of RAGE activity and uses thereof US Patent US10729695 Publication Date 8/4/2020
More Info.:Get all data from this article,  Assay Method
 
Advanced glycosylation end product-specific receptor
Name:Advanced glycosylation end product-specific receptor
Synonyms:AGER | RAGE | RAGE_HUMAN | Receptor for advanced glycosylation end products
Type:PROTEIN
Mol. Mass.:42800.11
Organism:Homo sapiens (Human)
Description:ChEMBL_1339877
Residue:404
Sequence:
MAAGTAVGAWVLVLSLWGAVVGAQNITARIGEPLVLKCKGAPKKPPQRLEWKLNTGRTEA
WKVLSPQGGGPWDSVARVLPNGSLFLPAVGIQDEGIFRCQAMNRNGKETKSNYRVRVYQI
PGKPEIVDSASELTAGVPNKVGTCVSEGSYPAGTLSWHLDGKPLVPNEKGVSVKEQTRRH
PETGLFTLQSELMVTPARGGDPRPTFSCSFSPGLPRHRALRTAPIQPRVWEPVPLEEVQL
VVEPEGGAVAPGGTVTLTCEVPAQPSPQIHWMKDGVPLPLPPSPVLILPEIGPQDQGTYS
CVATHSSHGPQESRAVSISIIEPGEEGPTAGSVGGSGLGTLALALGILGGLGTAALLIGV
ILWQRRQRRGEERKAPENQEEEEERAELNQSEEPEAGESSTGGP
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  Blast E-value cutoff:
BDBM453304
n/a
NameBDBM453304
Synonyms:US10729695, Compound CD-29
TypeSmall organic molecule
Emp. Form.C19H19N3O
Mol. Mass.305.3737
SMILESCc1nccn1CC(O)Cn1c2ccccc2c2ccccc12
Structure
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