| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM454326 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibit Human Recombinant Assay |
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| IC50 | >3000±n/a nM |
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| Citation |  Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Indole and azaindole haloallylamine derivative inhibitors of lysyl oxidases and uses thereof US Patent US10717734 Publication Date 7/21/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
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| Type: | Protein |
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| Mol. Mass.: | 58768.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27338 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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| BDBM454326 |
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| n/a |
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| Name | BDBM454326 |
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| Synonyms: | US10717734, Compound 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H28FN3O4S |
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| Mol. Mass. | 473.56 |
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| SMILES | COC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(Cc3ccc(cc3)S(=O)(=O)N(C)C)c2c1 |
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| Structure | 
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