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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cyclin-dependent kinase 9 | ||
| Ligand | BDBM454578 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Assay (ATP Concentration at Km) | ||
| IC50 | <3.00±n/a nM | ||
| Citation |  Barlaam, B; De Savi, C; Hawkins, J; Hird, A; Lamb, M; Pike, K; Vasbinder, M Chemical compounds US Patent US10717746 Publication Date 7/21/2020 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cyclin-dependent kinase 9 | |||
| Name: | Cyclin-dependent kinase 9 | ||
| Synonyms: | C-2K | CDC2L4 | CDK9 | CDK9_HUMAN | Cell division cycle 2-like protein kinase 4 | Cell division protein kinase 9 | Cyclin-Dependent Kinase 9 (CDK9) | Cyclin-dependent kinase 9 (CDK9) | Serine/threonine-protein kinase PITALRE | TAK | Tat-associated kinase complex catalytic subunit | ||
| Type: | Enzyme Subunit | ||
| Mol. Mass.: | 42789.13 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 372 | ||
| Sequence: |
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| BDBM454578 | |||
| n/a | |||
| Name | BDBM454578 | ||
| Synonyms: | US10717746, Example 58 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H21ClN4O2 | ||
| Mol. Mass. | 360.838 | ||
| SMILES | CC1(C)Cc2ncc(-c3cc(NC(=O)[C@@H]4C[C@H](O)C4)ncc3Cl)n2C1 |r,wD:14.13,16.16,(1.09,5.09,;.32,3.76,;1.81,3.36,;-.93,4.66,;-2.17,3.76,;-3.71,3.76,;-4.19,2.29,;-2.94,1.39,;-2.94,-.15,;-1.61,-.92,;-1.61,-2.46,;-.28,-3.23,;1.06,-2.46,;1.06,-.92,;2.39,-3.23,;3.88,-2.83,;4.28,-4.32,;5.61,-5.09,;2.79,-4.72,;-2.94,-3.23,;-4.28,-2.46,;-4.28,-.92,;-5.61,-.15,;-1.7,2.29,;-.16,2.29,)| | ||
| Structure | 
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