| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A1 |
|---|
| Ligand | BDBM464678 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Radioligand Binding Competition Assay |
|---|
| IC50 | 33.0±n/a nM |
|---|
| Citation |  Pham, SM; Chen, J; Ansari, A; Jadhavar, PS; Patil, VS; Khan, F; Ramachandran, SA; Agarwal, AK; Chakravarty, S 1,8-naphthyridinone compounds and uses thereof US Patent US10793561 Publication Date 10/6/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A1 |
|---|
| Name: | Adenosine receptor A1 |
|---|
| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 36520.92 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P30542 |
|---|
| Residue: | 326 |
|---|
| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
|
|
|
|---|
| BDBM464678 |
|---|
| n/a |
|---|
| Name | BDBM464678 |
|---|
| Synonyms: | US10793561, Compound 1.14 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H13N3O2 |
|---|
| Mol. Mass. | 339.3468 |
|---|
| SMILES | O=c1cc[nH]c2nc(-c3ccco3)c(cc12)-c1ccc2ncccc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
