Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM50240209 (CHEMBL4068526) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | <0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Integral BioSciences Pvt. Ltd Curated by ChEMBL | Assay Description Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic... | Bioorg Med Chem Lett 27: 2153-2160 (2017) Article DOI: 10.1016/j.bmcl.2017.03.064 BindingDB Entry DOI: 10.7270/Q2SX6GC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM50240227 (CHEMBL4084391) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Integral BioSciences Pvt. Ltd Curated by ChEMBL | Assay Description Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductase | Bioorg Med Chem Lett 27: 2153-2160 (2017) Article DOI: 10.1016/j.bmcl.2017.03.064 BindingDB Entry DOI: 10.7270/Q2SX6GC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549539 (US11306071, Compound 115 | US11306071, Compound 12...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549471 (US11306071, Compound 98) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549529 (US11306071, Compound 104) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM50240213 (CHEMBL4085366) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Integral BioSciences Pvt. Ltd Curated by ChEMBL | Assay Description Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic... | Bioorg Med Chem Lett 27: 2153-2160 (2017) Article DOI: 10.1016/j.bmcl.2017.03.064 BindingDB Entry DOI: 10.7270/Q2SX6GC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM50240224 (CHEMBL4095856) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Integral BioSciences Pvt. Ltd Curated by ChEMBL | Assay Description Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic... | Bioorg Med Chem Lett 27: 2153-2160 (2017) Article DOI: 10.1016/j.bmcl.2017.03.064 BindingDB Entry DOI: 10.7270/Q2SX6GC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549548 (US11306071, Compound 123) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549540 (US11306071, Compound 116 | US11306071, Compound 12...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549550 (US11306071, Compound 125 | US11306071, Compound 12...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549528 (US11306071, Compound 102 | US11306071, Compound 10...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549531 (US11306071, Compound 108) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549527 (US11306071, Compound 100) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM501684 (US11028058, Compound 1.309) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
NUVATION BIO INC. US Patent | Assay Description For the A2A adenosine receptor radioligand binding assay, the following modifications were made to the general protocol. GF/C filters (Perkin Elmer, ... | US Patent US11028058 (2021) BindingDB Entry DOI: 10.7270/Q23J3H46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549536 (US11306071, Compound 112) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM50240216 (CHEMBL4074076) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Integral BioSciences Pvt. Ltd Curated by ChEMBL | Assay Description Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic... | Bioorg Med Chem Lett 27: 2153-2160 (2017) Article DOI: 10.1016/j.bmcl.2017.03.064 BindingDB Entry DOI: 10.7270/Q2SX6GC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549552 (US11306071, Compound 126) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549528 (US11306071, Compound 102 | US11306071, Compound 10...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM50240226 (CHEMBL4065459) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Integral BioSciences Pvt. Ltd Curated by ChEMBL | Assay Description Inhibitory activity against HSV-1 Ribonucleoside diphosphate reductase was determined | Bioorg Med Chem Lett 27: 2153-2160 (2017) Article DOI: 10.1016/j.bmcl.2017.03.064 BindingDB Entry DOI: 10.7270/Q2SX6GC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Homo sapiens (Human)) | BDBM50199118 (CHEMBL3894825) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Integral BioSciences Pvt. Ltd Curated by ChEMBL | Assay Description Inhibition of HDAC6 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylation | Bioorg Med Chem Lett 26: 5222-5228 (2016) Article DOI: 10.1016/j.bmcl.2016.09.058 BindingDB Entry DOI: 10.7270/Q29W0HFD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549550 (US11306071, Compound 125 | US11306071, Compound 12...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM501676 (US11028058, Compound 1.271) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
NUVATION BIO INC. US Patent | Assay Description For the A2A adenosine receptor radioligand binding assay, the following modifications were made to the general protocol. GF/C filters (Perkin Elmer, ... | US Patent US11028058 (2021) BindingDB Entry DOI: 10.7270/Q23J3H46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM501677 (US11028058, Compound 1.292) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
NUVATION BIO INC. US Patent | Assay Description For the A2A adenosine receptor radioligand binding assay, the following modifications were made to the general protocol. GF/C filters (Perkin Elmer, ... | US Patent US11028058 (2021) BindingDB Entry DOI: 10.7270/Q23J3H46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549394 (US11306071, Compound 75) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM539111 (US11254670, Compound 1) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A second A2A adenosine receptor radioligand binding assay protocol was used. The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400... | Citation and Details BindingDB Entry DOI: 10.7270/Q2V98C8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280366 (2-(5-chloro-2-fluorophenyl)-5-cyclopropyl-N-{1H-py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280366 (2-(5-chloro-2-fluorophenyl)-5-cyclopropyl-N-{1H-py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280366 (2-(5-chloro-2-fluorophenyl)-5-cyclopropyl-N-{1H-py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280366 (2-(5-chloro-2-fluorophenyl)-5-cyclopropyl-N-{1H-py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549534 (US11306071, Compound 110) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM50405407 (CHEMBL5285361) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Inhibitory activity against Escherichia coli leader peptidase using substrate A | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM50405402 (CHEMBL5267945) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Inhibitory activity against Escherichia coli leader peptidase using substrate A | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549526 (US11306071, Compound 2-10) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549375 (US11306071, Compound 73) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM501679 (US11028058, Compound 1.290) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
NUVATION BIO INC. US Patent | Assay Description For the A2A adenosine receptor radioligand binding assay, the following modifications were made to the general protocol. GF/C filters (Perkin Elmer, ... | US Patent US11028058 (2021) BindingDB Entry DOI: 10.7270/Q23J3H46 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549399 (US11306071, Compound 76) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549538 (US11306071, Compound 114) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM539137 (US11254670, Compound 7) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description A second A2A adenosine receptor radioligand binding assay protocol was used. The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400... | Citation and Details BindingDB Entry DOI: 10.7270/Q2V98C8N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549525 (US11306071, Compound 2-6) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280370 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{1H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280369 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{7H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280370 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{1H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280370 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{1H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280369 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{7H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280369 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{7H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549549 (US11306071, Compound 124) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280369 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{7H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1B (Homo sapiens (Human)) | BDBM280370 (2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{1H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Medivation Technologies LLC US Patent | Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t... | US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549533 (US11306071, Compound 109) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM549545 (US11306071, Compound 120 | US11306071, Compound 12...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The protocol used adenosine A2a (human) membrane (PerkinElmer RBHA2AM400UA) at a concentration of 5 μg/well/100 μl and the radioligand [3H]... | Citation and Details BindingDB Entry DOI: 10.7270/Q21J9DZC | |||||||||||
More data for this Ligand-Target Pair |
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