BDBM50240216 CHEMBL4074076

SMILES: Cc1ccc(NC(=O)c2ccc(CN3CCNCC3)c(c2)C(F)(F)F)cc1NC(=O)c1cccc(c1)-c1cnn(C)c1

InChI Key: InChIKey=YXXUFRNFUJOIQQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240216   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50240216 (CHEMBL4074076) Show SMILES Cc1ccc(NC(=O)c2ccc(CN3CCNCC3)c(c2)C(F)(F)F)cc1NC(=O)c1cccc(c1)-c1cnn(C)c1 Show InChI InChI=1S/C31H31F3N6O2/c1-20-6-9-26(16-28(20)38-30(42)22-5-3-4-21(14-22)25-17-36-39(2)18-25)37-29(41)23-7-8-24(27(15-23)31(32,33)34)19-40-12-10-35-11-13-40/h3-9,14-18,35H,10-13,19H2,1-2H3,(H,37,41)(H,38,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Integral BioSciences Pvt. Ltd Curated by ChEMBL					Assay Description Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...				Bioorg Med Chem Lett 27: 2153-2160 (2017) Article DOI: 10.1016/j.bmcl.2017.03.064 BindingDB Entry DOI: 10.7270/Q2SX6GC2
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50240216 (CHEMBL4074076) Show SMILES Cc1ccc(NC(=O)c2ccc(CN3CCNCC3)c(c2)C(F)(F)F)cc1NC(=O)c1cccc(c1)-c1cnn(C)c1 Show InChI InChI=1S/C31H31F3N6O2/c1-20-6-9-26(16-28(20)38-30(42)22-5-3-4-21(14-22)25-17-36-39(2)18-25)37-29(41)23-7-8-24(27(15-23)31(32,33)34)19-40-12-10-35-11-13-40/h3-9,14-18,35H,10-13,19H2,1-2H3,(H,37,41)(H,38,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Integral BioSciences Pvt. Ltd Curated by ChEMBL					Assay Description Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...				Bioorg Med Chem Lett 27: 2153-2160 (2017) Article DOI: 10.1016/j.bmcl.2017.03.064 BindingDB Entry DOI: 10.7270/Q2SX6GC2
					More data for this Ligand-Target Pair