| Reaction Details |
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 | Report a problem with these data |
| Target | Indoleamine 2,3-dioxygenase 1 |
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| Ligand | BDBM168419 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | IDO Kynurenine Assay |
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| Temperature | 298.15±n/a K |
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| EC50 | 527±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC; Balog, JA; Huang, A; Chen, B; Chen, L; Seitz, SP; Hart, AC; Markwalder, JA Inhibitors of indoleamine 2,3-dioxygenase (IDO) US Patent US9675571 Publication Date 6/13/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Indoleamine 2,3-dioxygenase 1 |
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| Name: | Indoleamine 2,3-dioxygenase 1 |
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| Synonyms: | I23O1_HUMAN | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine 2,3-dioxygenase | Indoleamine-pyrrole 2,3-dioxygenase |
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| Type: | Enzyme |
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| Mol. Mass.: | 45330.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14902 |
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| Residue: | 403 |
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| Sequence: | MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE
KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLEL
PPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKV
IPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGN
PQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMP
PAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ
QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
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| BDBM168419 |
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| n/a |
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| Name | BDBM168419 |
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| Synonyms: | US9675571, 73 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H34F3N3O3 |
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| Mol. Mass. | 517.5831 |
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| SMILES | Cc1ccc(NC(=O)Nc2cc(ccc2N(CCCC(F)(F)F)C2CCCCC2)[C@H]2C[C@H]2C(O)=O)cc1 |r| |
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| Structure | 
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