Compile Data Set for Download or QSAR

Found 2634 hits with Last Name = 'hart' and Initial = 'ac'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142829 (US8940736, 391) Show SMILES Cc1nc(Nc2nc(Nc3ccc4n(C)nc(C#N)c4c3)nn3c(cnc23)[N+]#[C-])nn1C Show InChI InChI=1S/C19H15N13/c1-10-23-18(28-30(10)3)25-16-17-22-9-15(21-2)32(17)29-19(26-16)24-11-5-6-14-12(7-11)13(8-20)27-31(14)4/h5-7,9H,1,3-4H3,(H2,24,25,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142775 (US8940736, 7) Show SMILES OC1CCN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C20H18ClN9O/c21-17-15(5-11(7-22)6-16(17)29-4-3-14(31)10-29)26-20-27-18(25-12-1-2-12)19-24-9-13(8-23)30(19)28-20/h5-6,9,12,14,31H,1-4,10H2,(H2,25,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142816 (US8940736, 281) Show SMILES COC(=O)N[C@@H]1CCN(C[C@H]1OP(O)(O)=O)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H24ClN10O6P/c1-39-23(35)30-15-4-5-33(11-18(15)40-41(36,37)38)17-7-12(8-25)6-16(19(17)24)29-22-31-20(28-13-2-3-13)21-27-10-14(9-26)34(21)32-22/h6-7,10,13,15,18H,2-5,11H2,1H3,(H,30,35)(H2,36,37,38)(H2,28,29,31,32)/t15-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142774 (US8940736, 6) Show SMILES Cn1nc(C#N)c2cc(Nc3nc(NC4CC4)c4ncc(C#N)n4n3)ccc12 Show InChI InChI=1S/C18H14N10/c1-27-15-5-4-11(6-13(15)14(8-20)25-27)23-18-24-16(22-10-2-3-10)17-21-9-12(7-19)28(17)26-18/h4-6,9-10H,2-3H2,1H3,(H2,22,23,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142835 (US8940736, 402) Show SMILES OCc1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C17H13ClN8O/c18-14-10(8-27)3-9(5-19)4-13(14)23-17-24-15(22-11-1-2-11)16-21-7-12(6-20)26(16)25-17/h3-4,7,11,27H,1-2,8H2,(H2,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142792 (US8940736, 160) Show SMILES CS(=O)(=O)C1CCN(C1)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C24H25ClN10O2S/c1-38(36,37)18-4-5-33(13-18)17-11-34(12-17)20-7-14(8-26)6-19(21(20)25)30-24-31-22(29-15-2-3-15)23-28-10-16(9-27)35(23)32-24/h6-7,10,15,17-18H,2-5,11-13H2,1H3,(H2,29,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142777 (US8940736, 49) Show SMILES Clc1c(NN2CCOCC2)cc(cc1Nc1nc(NC2CC2)c2ncc(C#N)n2n1)C#N Show InChI InChI=1S/C20H19ClN10O/c21-17-15(7-12(9-22)8-16(17)28-30-3-5-32-6-4-30)26-20-27-18(25-13-1-2-13)19-24-11-14(10-23)31(19)29-20/h7-8,11,13,28H,1-6H2,(H2,25,26,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142829 (US8940736, 391) Show SMILES Cc1nc(Nc2nc(Nc3ccc4n(C)nc(C#N)c4c3)nn3c(cnc23)[N+]#[C-])nn1C Show InChI InChI=1S/C19H15N13/c1-10-23-18(28-30(10)3)25-16-17-22-9-15(21-2)32(17)29-19(26-16)24-11-5-6-14-12(7-11)13(8-20)27-31(14)4/h5-7,9H,1,3-4H3,(H2,24,25,26,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.130	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142822 (US8940736, 328) Show SMILES CCNc1nc(Nc2cc(cc(N3CC[C@H](NC(=O)OC)[C@@H](O)C3)c2Cl)C#N)nn2c(cnc12)[N+]#[C-] |r| Show InChI InChI=1S/C22H23ClN10O3/c1-4-26-19-20-27-10-17(25-2)33(20)31-21(30-19)28-14-7-12(9-24)8-15(18(14)23)32-6-5-13(16(34)11-32)29-22(35)36-3/h7-8,10,13,16,34H,4-6,11H2,1,3H3,(H,29,35)(H2,26,28,30,31)/t13-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.130	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142817 (US8940736, 285) Show SMILES COC(=O)N[C@@H]1CCN(C[C@@H]1F)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H22ClFN10O2/c1-37-23(36)31-16-4-5-34(11-15(16)25)18-7-12(8-26)6-17(19(18)24)30-22-32-20(29-13-2-3-13)21-28-10-14(9-27)35(21)33-22/h6-7,10,13,15-16H,2-5,11H2,1H3,(H,31,36)(H2,29,30,32,33)/t15-,16+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142774 (US8940736, 6) Show SMILES Cn1nc(C#N)c2cc(Nc3nc(NC4CC4)c4ncc(C#N)n4n3)ccc12 Show InChI InChI=1S/C18H14N10/c1-27-15-5-4-11(6-13(15)14(8-20)25-27)23-18-24-16(22-10-2-3-10)17-21-9-12(7-19)28(17)26-18/h4-6,9-10H,2-3H2,1H3,(H2,22,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142784 (US8940736, 117) Show SMILES Clc1c(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)cc(cc1N1CCC(CC1)NC1CCS(=O)(=O)C1)C#N Show InChI InChI=1S/C25H27ClN10O2S/c26-22-20(32-25-33-23(31-16-1-2-16)24-29-13-19(12-28)36(24)34-25)9-15(11-27)10-21(22)35-6-3-17(4-7-35)30-18-5-8-39(37,38)14-18/h9-10,13,16-18,30H,1-8,14H2,(H2,31,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142834 (US8940736, 399) Show SMILES Clc1c(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)cc(cc1C=C)C#N Show InChI InChI=1S/C18H13ClN8/c1-2-11-5-10(7-20)6-14(15(11)19)24-18-25-16(23-12-3-4-12)17-22-9-13(8-21)27(17)26-18/h2,5-6,9,12H,1,3-4H2,(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142806 (US8940736, 229) Show SMILES CC(=O)N1CCC(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C23H22ClN9O/c1-13(34)32-6-4-15(5-7-32)18-8-14(10-25)9-19(20(18)24)29-23-30-21(28-16-2-3-16)22-27-12-17(11-26)33(22)31-23/h8-9,12,15-16H,2-7H2,1H3,(H2,28,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142835 (US8940736, 402) Show SMILES OCc1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C17H13ClN8O/c18-14-10(8-27)3-9(5-19)4-13(14)23-17-24-15(22-11-1-2-11)16-21-7-12(6-20)26(16)25-17/h3-4,7,11,27H,1-2,8H2,(H2,22,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142775 (US8940736, 7) Show SMILES OC1CCN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C20H18ClN9O/c21-17-15(5-11(7-22)6-16(17)29-4-3-14(31)10-29)26-20-27-18(25-12-1-2-12)19-24-9-13(8-23)30(19)28-20/h5-6,9,12,14,31H,1-4,10H2,(H2,25,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.170	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142778 (US8940736, 55) Show SMILES Clc1c(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)cc(cc1N1CCN(CC1)C1CCOC1)C#N Show InChI InChI=1S/C24H25ClN10O/c25-21-19(30-24-31-22(29-16-1-2-16)23-28-13-18(12-27)35(23)32-24)9-15(11-26)10-20(21)34-6-4-33(5-7-34)17-3-8-36-14-17/h9-10,13,16-17H,1-8,14H2,(H2,29,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142793 (US8940736, 161) Show SMILES COC1CCN(C1)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C24H25ClN10O/c1-36-18-4-5-33(13-18)17-11-34(12-17)20-7-14(8-26)6-19(21(20)25)30-24-31-22(29-15-2-3-15)23-28-10-16(9-27)35(23)32-24/h6-7,10,15,17-18H,2-5,11-13H2,1H3,(H2,29,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142806 (US8940736, 229) Show SMILES CC(=O)N1CCC(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C23H22ClN9O/c1-13(34)32-6-4-15(5-7-32)18-8-14(10-25)9-19(20(18)24)29-23-30-21(28-16-2-3-16)22-27-12-17(11-26)33(22)31-23/h8-9,12,15-16H,2-7H2,1H3,(H2,28,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142818 (US8940736, 313) Show SMILES FC1CN(CCN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc([N+]#[C-])n3n2)c1Cl)C#N)C1COC1 Show InChI InChI=1S/C24H24ClFN10O/c1-28-20-9-29-23-22(30-16-2-3-16)32-24(33-36(20)23)31-18-6-14(8-27)7-19(21(18)25)35-5-4-34(10-15(26)11-35)17-12-37-13-17/h6-7,9,15-17H,2-5,10-13H2,(H2,30,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142832 (US8940736, 395) Show SMILES CCNc1nc(Nc2ccc3n(nc(C#N)c3c2)C2CCN(C[C@@H](C)O)CC2)nn2c(cnc12)C#N |r| Show InChI InChI=1S/C24H27N11O/c1-3-27-22-23-28-13-18(11-25)35(23)32-24(30-22)29-16-4-5-21-19(10-16)20(12-26)31-34(21)17-6-8-33(9-7-17)14-15(2)36/h4-5,10,13,15,17,36H,3,6-9,14H2,1-2H3,(H2,27,29,30,32)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142832 (US8940736, 395) Show SMILES CCNc1nc(Nc2ccc3n(nc(C#N)c3c2)C2CCN(C[C@@H](C)O)CC2)nn2c(cnc12)C#N |r| Show InChI InChI=1S/C24H27N11O/c1-3-27-22-23-28-13-18(11-25)35(23)32-24(30-22)29-16-4-5-21-19(10-16)20(12-26)31-34(21)17-6-8-33(9-7-17)14-15(2)36/h4-5,10,13,15,17,36H,3,6-9,14H2,1-2H3,(H2,27,29,30,32)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142784 (US8940736, 117) Show SMILES Clc1c(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)cc(cc1N1CCC(CC1)NC1CCS(=O)(=O)C1)C#N Show InChI InChI=1S/C25H27ClN10O2S/c26-22-20(32-25-33-23(31-16-1-2-16)24-29-13-19(12-28)36(24)34-25)9-15(11-27)10-21(22)35-6-3-17(4-7-35)30-18-5-8-39(37,38)14-18/h9-10,13,16-18,30H,1-8,14H2,(H2,31,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142836 (US8940736, 408) Show SMILES CCNc1nc(Nc2cc(cc(N3CCN(CC3)C3COC3)c2Cl)C#N)nn2c(cnc12)C#N Show InChI InChI=1S/C22H23ClN10O/c1-2-26-20-21-27-11-15(10-25)33(21)30-22(29-20)28-17-7-14(9-24)8-18(19(17)23)32-5-3-31(4-6-32)16-12-34-13-16/h7-8,11,16H,2-6,12-13H2,1H3,(H2,26,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142802 (US8940736, 207) Show SMILES CN1CCC(=CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |c:4| Show InChI InChI=1S/C22H20ClN9/c1-31-6-4-14(5-7-31)17-8-13(10-24)9-18(19(17)23)28-22-29-20(27-15-2-3-15)21-26-12-16(11-25)32(21)30-22/h4,8-9,12,15H,2-3,5-7H2,1H3,(H2,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142834 (US8940736, 399) Show SMILES Clc1c(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)cc(cc1C=C)C#N Show InChI InChI=1S/C18H13ClN8/c1-2-11-5-10(7-20)6-14(15(11)19)24-18-25-16(23-12-3-4-12)17-22-9-13(8-21)27(17)26-18/h2,5-6,9,12H,1,3-4H2,(H2,23,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142777 (US8940736, 49) Show SMILES Clc1c(NN2CCOCC2)cc(cc1Nc1nc(NC2CC2)c2ncc(C#N)n2n1)C#N Show InChI InChI=1S/C20H19ClN10O/c21-17-15(7-12(9-22)8-16(17)28-30-3-5-32-6-4-30)26-20-27-18(25-13-1-2-13)19-24-11-14(10-23)31(19)29-20/h7-8,11,13,28H,1-6H2,(H2,25,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142792 (US8940736, 160) Show SMILES CS(=O)(=O)C1CCN(C1)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C24H25ClN10O2S/c1-38(36,37)18-4-5-33(13-18)17-11-34(12-17)20-7-14(8-26)6-19(21(20)25)30-24-31-22(29-15-2-3-15)23-28-10-16(9-27)35(23)32-24/h6-7,10,15,17-18H,2-5,11-13H2,1H3,(H2,29,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.240	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142820 (US8940736, 319) Show SMILES CC(=O)N1CC(C1)N1CCC(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C26H27ClN10O/c1-15(38)36-13-20(14-36)35-6-4-17(5-7-35)21-8-16(10-28)9-22(23(21)27)32-26-33-24(31-18-2-3-18)25-30-12-19(11-29)37(25)34-26/h8-9,12,17-18,20H,2-7,13-14H2,1H3,(H2,31,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.25	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142799 (US8940736, 179) Show SMILES O[C@@H]1CN(CC[C@H]1NC(=O)OC1COC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C25H25ClN10O4/c26-21-18(31-24-33-22(30-14-1-2-14)23-29-9-15(8-28)36(23)34-24)5-13(7-27)6-19(21)35-4-3-17(20(37)10-35)32-25(38)40-16-11-39-12-16/h5-6,9,14,16-17,20,37H,1-4,10-12H2,(H,32,38)(H2,30,31,33,34)/t17-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.260	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142831 (US8940736, 394) Show SMILES CCNc1nc(Nc2ccc3n(nc(C#N)c3c2)C2CCN(C[C@H](C)O)CC2)nn2c(cnc12)C#N |r| Show InChI InChI=1S/C24H27N11O/c1-3-27-22-23-28-13-18(11-25)35(23)32-24(30-22)29-16-4-5-21-19(10-16)20(12-26)31-34(21)17-6-8-33(9-7-17)14-15(2)36/h4-5,10,13,15,17,36H,3,6-9,14H2,1-2H3,(H2,27,29,30,32)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142796 (US8940736, 173) Show SMILES COC(=O)N[C@@H]1CCN(C[C@H]1O)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H23ClN10O3/c1-37-23(36)30-15-4-5-33(11-18(15)35)17-7-12(8-25)6-16(19(17)24)29-22-31-20(28-13-2-3-13)21-27-10-14(9-26)34(21)32-22/h6-7,10,13,15,18,35H,2-5,11H2,1H3,(H,30,36)(H2,28,29,31,32)/t15-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142807 (US8940736, 238) Show SMILES Clc1c(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)cc(cc1C1CCN(CC1)C(=O)OC1COC1)C#N Show InChI InChI=1S/C25H24ClN9O3/c26-21-19(15-3-5-34(6-4-15)25(36)38-18-12-37-13-18)7-14(9-27)8-20(21)31-24-32-22(30-16-1-2-16)23-29-11-17(10-28)35(23)33-24/h7-8,11,15-16,18H,1-6,12-13H2,(H2,30,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142795 (US8940736, 167) Show SMILES OC1CN(C1)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C22H21ClN10O/c23-19-17(3-12(5-24)4-18(19)32-8-15(9-32)31-10-16(34)11-31)28-22-29-20(27-13-1-2-13)21-26-7-14(6-25)33(21)30-22/h3-4,7,13,15-16,34H,1-2,8-11H2,(H2,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142831 (US8940736, 394) Show SMILES CCNc1nc(Nc2ccc3n(nc(C#N)c3c2)C2CCN(C[C@H](C)O)CC2)nn2c(cnc12)C#N |r| Show InChI InChI=1S/C24H27N11O/c1-3-27-22-23-28-13-18(11-25)35(23)32-24(30-22)29-16-4-5-21-19(10-16)20(12-26)31-34(21)17-6-8-33(9-7-17)14-15(2)36/h4-5,10,13,15,17,36H,3,6-9,14H2,1-2H3,(H2,27,29,30,32)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142816 (US8940736, 281) Show SMILES COC(=O)N[C@@H]1CCN(C[C@H]1OP(O)(O)=O)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H24ClN10O6P/c1-39-23(35)30-15-4-5-33(11-18(15)40-41(36,37)38)17-7-12(8-25)6-16(19(17)24)29-22-31-20(28-13-2-3-13)21-27-10-14(9-26)34(21)32-22/h6-7,10,13,15,18H,2-5,11H2,1H3,(H,30,35)(H2,36,37,38)(H2,28,29,31,32)/t15-,18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142794 (US8940736, 163) Show SMILES COC(=O)N[C@@H]1CN(C[C@H]1C)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C26H28ClN11O2/c1-14-10-36(13-20(14)33-26(39)40-2)18-11-37(12-18)21-6-15(7-28)5-19(22(21)27)32-25-34-23(31-16-3-4-16)24-30-9-17(8-29)38(24)35-25/h5-6,9,14,16,18,20H,3-4,10-13H2,1-2H3,(H,33,39)(H2,31,32,34,35)/t14-,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142820 (US8940736, 319) Show SMILES CC(=O)N1CC(C1)N1CCC(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C26H27ClN10O/c1-15(38)36-13-20(14-36)35-6-4-17(5-7-35)21-8-16(10-28)9-22(23(21)27)32-26-33-24(31-18-2-3-18)25-30-12-19(11-29)37(25)34-26/h8-9,12,17-18,20H,2-7,13-14H2,1H3,(H2,31,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142779 (US8940736, 57) Show SMILES C[C@@H](O)CN1CCN(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H25ClN10O/c1-14(35)13-32-4-6-33(7-5-32)19-9-15(10-25)8-18(20(19)24)29-23-30-21(28-16-2-3-16)22-27-12-17(11-26)34(22)31-23/h8-9,12,14,16,35H,2-7,13H2,1H3,(H2,28,29,30,31)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142778 (US8940736, 55) Show SMILES Clc1c(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)cc(cc1N1CCN(CC1)C1CCOC1)C#N Show InChI InChI=1S/C24H25ClN10O/c25-21-19(30-24-31-22(29-16-1-2-16)23-28-13-18(12-27)35(23)32-24)9-15(11-26)10-20(21)34-6-4-33(5-7-34)17-3-8-36-14-17/h9-10,13,16-17H,1-8,14H2,(H2,29,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.290	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142818 (US8940736, 313) Show SMILES FC1CN(CCN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc([N+]#[C-])n3n2)c1Cl)C#N)C1COC1 Show InChI InChI=1S/C24H24ClFN10O/c1-28-20-9-29-23-22(30-16-2-3-16)32-24(33-36(20)23)31-18-6-14(8-27)7-19(21(18)25)35-5-4-34(10-15(26)11-35)17-12-37-13-17/h6-7,9,15-17H,2-5,10-13H2,(H2,30,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.290	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM50511306 (CHEMBL4470115) Show SMILES Nc1ccc(nc1)C#Cc1c(N)nccc1Oc1ccc(NC(=O)c2cccn(-c3ccc(F)cc3)c2=O)cc1F Show InChI InChI=1S/C30H20F2N6O3/c31-18-3-9-22(10-4-18)38-15-1-2-24(30(38)40)29(39)37-21-8-12-27(25(32)16-21)41-26-13-14-35-28(34)23(26)11-7-20-6-5-19(33)17-36-20/h1-6,8-10,12-17H,33H2,(H2,34,35)(H,37,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research & Development Curated by ChEMBL					Assay Description Displacement of fluorescein labeled probe from full length human GST-tagged RIPK3 expressed in Sf9 cells incubated for 60 mins by HTRF assay				ACS Med Chem Lett 11: 266-271 (2020) Article DOI: 10.1021/acsmedchemlett.9b00065 BindingDB Entry DOI: 10.7270/Q2VM4GKH
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142790 (US8940736, 133) Show SMILES O[C@H]1C[C@H](C1)NC1CCN(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r,wU:3.5,1.0,(10.45,-1.86,;9.11,-2.63,;8.72,-4.11,;7.23,-3.72,;7.63,-2.23,;5.89,-4.49,;4.56,-3.72,;3.23,-4.49,;1.89,-3.72,;1.89,-2.18,;3.23,-1.41,;4.56,-2.18,;.56,-1.41,;.56,.13,;-.77,.9,;-2.11,.13,;-2.11,-1.41,;-3.44,-2.18,;-4.78,-1.41,;-4.78,.13,;-6.11,.9,;-6.11,2.44,;-7.44,3.21,;-8.21,4.55,;-8.98,3.21,;-7.44,.13,;-8.91,.61,;-9.81,-.64,;-8.91,-1.88,;-9.68,-3.21,;-10.45,-4.55,;-7.44,-1.41,;-6.11,-2.18,;-.77,-2.18,;-.77,-3.72,;-.77,2.44,;-.77,3.98,)| Show InChI InChI=1S/C25H27ClN10O/c26-22-20(32-25-33-23(31-15-1-2-15)24-29-13-18(12-28)36(24)34-25)7-14(11-27)8-21(22)35-5-3-16(4-6-35)30-17-9-19(37)10-17/h7-8,13,15-17,19,30,37H,1-6,9-10H2,(H2,31,32,33,34)/t17-,19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142779 (US8940736, 57) Show SMILES C[C@@H](O)CN1CCN(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H25ClN10O/c1-14(35)13-32-4-6-33(7-5-32)19-9-15(10-25)8-18(20(19)24)29-23-30-21(28-16-2-3-16)22-27-12-17(11-26)34(22)31-23/h8-9,12,14,16,35H,2-7,13H2,1H3,(H2,28,29,30,31)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142795 (US8940736, 167) Show SMILES OC1CN(C1)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C22H21ClN10O/c23-19-17(3-12(5-24)4-18(19)32-8-15(9-32)31-10-16(34)11-31)28-22-29-20(27-13-1-2-13)21-26-7-14(6-25)33(21)30-22/h3-4,7,13,15-16,34H,1-2,8-11H2,(H2,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142793 (US8940736, 161) Show SMILES COC1CCN(C1)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C24H25ClN10O/c1-36-18-4-5-33(13-18)17-11-34(12-17)20-7-14(8-26)6-19(21(20)25)30-24-31-22(29-15-2-3-15)23-28-10-16(9-27)35(23)32-24/h6-7,10,15,17-18H,2-5,11-13H2,1H3,(H2,29,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142802 (US8940736, 207) Show SMILES CN1CCC(=CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |c:4| Show InChI InChI=1S/C22H20ClN9/c1-31-6-4-14(5-7-31)17-8-13(10-24)9-18(19(17)23)28-22-29-20(27-15-2-3-15)21-26-12-16(11-25)32(21)30-22/h4,8-9,12,15H,2-3,5-7H2,1H3,(H2,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM142797 (US8940736, 174) Show SMILES COC(=O)N[C@H]1CCN(C[C@@H]1O)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H23ClN10O3/c1-37-23(36)30-15-4-5-33(11-18(15)35)17-7-12(8-25)6-16(19(17)24)29-22-31-20(28-13-2-3-13)21-27-10-14(9-26)34(21)32-22/h6-7,10,13,15,18,35H,2-5,11H2,1H3,(H,30,36)(H2,28,29,31,32)/t15-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.350	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142827 (US8940736, 382) Show SMILES CN1CCN(CC1)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc([N+]#[C-])n3n2)c1F)C#N Show InChI InChI=1S/C24H26FN11/c1-27-20-12-28-23-22(29-16-3-4-16)31-24(32-36(20)23)30-18-9-15(11-26)10-19(21(18)25)35-13-17(14-35)34-7-5-33(2)6-8-34/h9-10,12,16-17H,3-8,13-14H2,2H3,(H2,29,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.390	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142796 (US8940736, 173) Show SMILES COC(=O)N[C@@H]1CCN(C[C@H]1O)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H23ClN10O3/c1-37-23(36)30-15-4-5-33(11-18(15)35)17-7-12(8-25)6-16(19(17)24)29-22-31-20(28-13-2-3-13)21-27-10-14(9-26)34(21)32-22/h6-7,10,13,15,18,35H,2-5,11H2,1H3,(H,30,36)(H2,28,29,31,32)/t15-,18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.410	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 2634 total )  |  Next  |  Last  >>

Jump to: