| Reaction Details |
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 | Report a problem with these data |
| Target | WD repeat-containing protein 5 |
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| Ligand | BDBM473342 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TR-FRET Binding Assay |
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| Ki | <0.100±n/a nM |
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| Citation |  Alvarado, JR; Stauffer, SR; Gogliotti, RD; Han, C; Meyers, KM; Tian, J; Macdonald, JD; Fesik, SW; Lee, T WDR5 inhibitors and modulators US Patent US10844044 Publication Date 11/24/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| WD repeat-containing protein 5 |
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| Name: | WD repeat-containing protein 5 |
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| Synonyms: | BIG3 | WD repeat-containing protein 5 | WD repeat-containing protein 5 (WDR5) | WD repeat-containing protein 5 (WRD5) | WDR5 | WDR5_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 36597.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P61964 |
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| Residue: | 334 |
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| Sequence: | MATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWL
ASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK
CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN
RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKL
WDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGH
TDVVISTACHPTENIIASAALENDKTIKLWKSDC
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| BDBM473342 |
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| n/a |
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| Name | BDBM473342 |
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| Synonyms: | US10844044, Example 220 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H29F3N6O |
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| Mol. Mass. | 522.5647 |
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| SMILES | Cc1cccc(c1)C1(CCC1)NC(=O)c1cc(Cn2ccn(C)c2=N)cc(c1)-c1cn(C)nc1C(F)(F)F |
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| Structure | 
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