| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase [H274Y] |
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| Ligand | BDBM482724 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Activity assay for influenza virus neuraminidase |
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| IC50 | 5.5±n/a nM |
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| Citation |  Zhang, J; Wang, K; Liu, Y; Li, D Cyclohexene compounds and use thereof US Patent US10919856 Publication Date 2/16/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase [H274Y] |
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| Name: | Neuraminidase [H274Y] |
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| Synonyms: | NA | NRAM_I67A0 | Neuraminidase A (H274Y) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52157.78 |
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| Organism: | Influenza A virus (A/Tokyo/3/67(H2N2)) |
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| Description: | P06820[H274Y] |
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| Residue: | 469 |
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| Sequence: | MNPNQKIITIGSVSLTIATVCFLMQIAILVTTVTLHFKQHECDSPASNQVMPCEPIIIER
NITEIVYLNNTTIEKEICPKVVEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREP
YVSCDPVKCYQFALGQGTTLDNKHSNDTVHDRIPHRTLLMNELGVPFHLGTRQVCIAWSS
SSCHDGKAWLHVCITGDDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVV
MTDGSASGRADTRILFIEEGKIVHISPLAGSAQYVEECSCYPRYPGVRCICRDNWKGSNR
PVVDINMEDYSIDSSYVCSGLVGDTPRNDDRSSNSNCRNPNNERGTQGVKGWAFDNGNDL
WMGRTISKDLRSGYETFKVIGGWSTPNSKSQINRQVIVDSDNRSGYSGIFSVEGKSCINR
CFYVELIRGRKQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI
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| BDBM482724 |
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| n/a |
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| Name | BDBM482724 |
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| Synonyms: | US10919856, Example 9 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H32N4O6 |
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| Mol. Mass. | 412.4806 |
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| SMILES | CN(C)C(=O)OCCO[C@H]1CCCN(C1)[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O |r,c:17| |
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| Structure | 
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