| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
|---|
| Ligand | BDBM301739 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Pharmacological Assay |
|---|
| EC50 | 12.0±n/a nM |
|---|
| Citation |  Eckhardt, M; Frattini, S; Langkopf, E; Wagner, H Indanyloxydihydrobenzofuranylacetic acids US Patent US9597310 Publication Date 3/21/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Free fatty acid receptor 1 |
|---|
| Name: | Free fatty acid receptor 1 |
|---|
| Synonyms: | FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 31473.32 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | O14842 |
|---|
| Residue: | 300 |
|---|
| Sequence: | MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
|
|
|
|---|
| BDBM301739 |
|---|
| n/a |
|---|
| Name | BDBM301739 |
|---|
| Synonyms: | US9597310, 29 | {(S)-6-[(R)-7-Fluoro-4-{5-[(S)-tetrahydro-furan-3-yloxy}-pyridin-2-yloxy}-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H28FNO7 |
|---|
| Mol. Mass. | 521.5335 |
|---|
| SMILES | COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3c(F)ccc4Oc3ccc(O[C@H]4CCOC4)cn3)ccc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
