| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
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| Ligand | BDBM301774 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Pharmacological Assay |
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| EC50 | 27.0±n/a nM |
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| Citation |  Eckhardt, M; Frattini, S; Langkopf, E; Wagner, H Indanyloxydihydrobenzofuranylacetic acids US Patent US9597310 Publication Date 3/21/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 1 |
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| Name: | Free fatty acid receptor 1 |
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| Synonyms: | FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 31473.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O14842 |
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| Residue: | 300 |
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| Sequence: | MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLP
LKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRP
CYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAG
PARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPY
NASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
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| BDBM301774 |
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| n/a |
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| Name | BDBM301774 |
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| Synonyms: | ((S)-6-{(R)-7-Fluoro-4-[1-(3-hydroxy-3-methylbutyl)-1H-indazol-6-yloxy]-indan-1-yloxy}-2,3-dihydrobenzofuran-3-yl)-acetic acid methyl ester | US9597310, 64 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H33FN2O6 |
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| Mol. Mass. | 560.6126 |
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| SMILES | COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3c(F)ccc4Oc3ccc4cnn(CCC(C)(C)O)c4c3)ccc12 |r| |
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| Structure | 
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