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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Non-receptor tyrosine-protein kinase TYK2 | ||
| Ligand | BDBM50243842 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Caliper Enzyme Assay | ||
| IC50 | 2203±n/a nM | ||
| Citation |  Vazquez, ML; Kaila, N; Tuttle, JB; Verhoest, PR; Reese, MR; Coffman, KJ; Samad, T; Duerr, JM; Sciabola, S; Parikh, MD Pyrrolo[2,3-d]pyrimidine derivatives US Patent US10966980 Publication Date 4/6/2021 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Non-receptor tyrosine-protein kinase TYK2 | |||
| Name: | Non-receptor tyrosine-protein kinase TYK2 | ||
| Synonyms: | Non-receptor tyrosine-protein kinase TYK2 (TYK2) | TYK2 | TYK2_HUMAN | Tyrosine-protein kinase TYK2 | ||
| Type: | Protein | ||
| Mol. Mass.: | 133666.03 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P29597 | ||
| Residue: | 1187 | ||
| Sequence: |
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| BDBM50243842 | |||
| n/a | |||
| Name | BDBM50243842 | ||
| Synonyms: | CHEMBL4066404 | US10966980, Example 80 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H27N5O2S | ||
| Mol. Mass. | 365.494 | ||
| SMILES | CCCCN(C)S(=O)(=O)C[C@H]1C[C@H](C1)N(C)c1ncnc2[nH]ccc12 |r,wD:12.14,10.9,(20.04,-11.87,;18.7,-12.63,;17.37,-11.86,;16.03,-12.62,;14.69,-11.84,;14.7,-10.3,;13.35,-12.61,;14.12,-13.94,;12.58,-13.93,;12.02,-11.85,;10.69,-12.62,;9.2,-12.23,;8.81,-13.72,;10.3,-14.11,;7.48,-14.5,;6.15,-13.73,;7.49,-16.04,;6.16,-16.81,;6.15,-18.35,;7.49,-19.12,;8.83,-18.34,;10.3,-18.81,;11.2,-17.56,;10.29,-16.31,;8.82,-16.8,)| | ||
| Structure | 
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