Reaction Details | |||
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Target | Leucyl-cystinyl aminopeptidase | ||
Ligand | BDBM271258 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Inhibition Activity Assay | ||
IC50 | 1.60±n/a nM | ||
Citation | Kawaguchi, K; Ishihata, A; Inagaki, Y; Tsuchiya, K; Hanadate, T; Kanai, A; Kaizawa, H; Kazami, J; Morikawa, H; Hiramoto, M; Enjo, K; Takamatsu, H Pyridine derivative US Patent US10975091 Publication Date 4/13/2021 | ||
More Info.: | Get all data from this article, Assay Method | ||
Leucyl-cystinyl aminopeptidase | |||
Name: | Leucyl-cystinyl aminopeptidase | ||
Synonyms: | Aminopeptidase | Aminopeptidase (P-LAP) | Cystinyl aminopeptidase | IRAP | Insulin-regulated membrane aminopeptidase | Insulin-responsive aminopeptidase | LCAP_HUMAN | LNPEP | Leucyl-cystinyl aminopeptidase, pregnancy serum form | OTASE | Oxytocinase | P-LAP | Placental leucine aminopeptidase | ||
Type: | PROTEIN | ||
Mol. Mass.: | 117334.10 | ||
Organism: | Homo sapiens (Human) | ||
Description: | ChEMBL_1473494 | ||
Residue: | 1025 | ||
Sequence: |
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BDBM271258 | |||
n/a | |||
Name | BDBM271258 | ||
Synonyms: | US10059720, Example 73 | US10975091, Example 73 | ||
Type | Small organic molecule | ||
Emp. Form. | C21H34N2O4 | ||
Mol. Mass. | 378.5057 | ||
SMILES | CC(C)C[C@H](N)[C@](O)(Cc1cc(O[C@H]2CC[C@H](C)CC2)c(C)cn1)C(O)=O |r,wU:6.7,4.4,16.16,wD:13.12,6.6,(-7.34,-2.31,;-6,-3.08,;-6,-4.62,;-4.67,-2.31,;-3.33,-3.08,;-3.33,-4.62,;-2,-2.31,;-1.23,-.98,;-.67,-3.08,;.67,-2.31,;.67,-.77,;2,,;2,1.54,;3.33,2.31,;4.67,1.54,;6,2.31,;6,3.85,;7.34,4.62,;4.67,4.62,;3.33,3.85,;3.33,-.77,;4.67,,;3.33,-2.31,;2,-3.08,;-2.77,-.98,;-4.31,-.98,;-2,.36,)| | ||
Structure |