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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Leucyl-cystinyl aminopeptidase | ||
| Ligand | BDBM271290 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Activity Assay | ||
| IC50 | 0.620±n/a nM | ||
| Citation |  Kawaguchi, K; Ishihata, A; Inagaki, Y; Tsuchiya, K; Hanadate, T; Kanai, A; Kaizawa, H; Kazami, J; Morikawa, H; Hiramoto, M; Enjo, K; Takamatsu, H Pyridine derivative US Patent US10975091 Publication Date 4/13/2021 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Leucyl-cystinyl aminopeptidase | |||
| Name: | Leucyl-cystinyl aminopeptidase | ||
| Synonyms: | Cystinyl aminopeptidase | GP160 | Insulin-regulated membrane aminopeptidase | Insulin-responsive aminopeptidase | Irap | LCAP_RAT | Leucyl-cystinyl aminopeptidase | Lnpep | Otase | Oxytocinase | P-LAP | Placental leucine aminopeptidase | Vesicle protein of 165 kDa | Vp165 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 117179.39 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_98523 | ||
| Residue: | 1025 | ||
| Sequence: |
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| BDBM271290 | |||
| n/a | |||
| Name | BDBM271290 | ||
| Synonyms: | US10059720, Example 105 | US10975091, Example 105 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H30N2O4S | ||
| Mol. Mass. | 382.518 | ||
| SMILES | CCSC[C@H](N)[C@](O)(Cc1cc(O[C@H]2CC[C@H](C)CC2)ccn1)C(O)=O |r,wU:6.7,4.4,16.16,wD:13.12,6.6,(-8,-3.08,;-6.67,-2.31,;-5.33,-3.08,;-4,-2.31,;-2.67,-3.08,;-2.67,-4.62,;-1.33,-2.31,;-.56,-.98,;,-3.08,;1.33,-2.31,;1.33,-.77,;2.67,,;2.67,1.54,;4,2.31,;5.33,1.54,;6.67,2.31,;6.67,3.85,;8,4.62,;5.33,4.62,;4,3.85,;4,-.77,;4,-2.31,;2.67,-3.08,;-2.1,-.98,;-3.59,-1.37,;-1.33,.36,)| | ||
| Structure | 
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