| Reaction Details |
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 | Report a problem with these data |
| Target | Ribose-phosphate pyrophosphokinase 1 |
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| Ligand | BDBM493400 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | PRS Enzyme Activity Inhibition Experiment |
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| IC50 | <100±n/a nM |
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| Citation |  Lee, B; Cho, M; Lee, H; Jung, M; Oh, Y Heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same US Patent US10981917 Publication Date 4/20/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Ribose-phosphate pyrophosphokinase 1 |
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| Name: | Ribose-phosphate pyrophosphokinase 1 |
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| Synonyms: | PRPS1 | PRPS1_HUMAN | Ribose-phosphate pyrophosphokinase I |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34836.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_156521 |
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| Residue: | 318 |
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| Sequence: | MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGC
GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG
ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTS
IADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG
ATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAI
RRTHNGESVSYLFSHVPL
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| BDBM493400 |
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| n/a |
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| Name | BDBM493400 |
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| Synonyms: | US10981917, Example 101 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23ClN6OS |
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| Mol. Mass. | 442.965 |
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| SMILES | O[C@H]1CCCN[C@@H]1CCCn1cnc2cc(Cl)cc(-c3cnn(c3)-c3nccs3)c12 |r| |
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| Structure | 
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