| Reaction Details |
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 | Report a problem with these data |
| Target | Ribose-phosphate pyrophosphokinase 1 |
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| Ligand | BDBM493485 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | PRS Enzyme Activity Inhibition Experiment |
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| IC50 | 300±n/a nM |
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| Citation |  Lee, B; Cho, M; Lee, H; Jung, M; Oh, Y Heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same US Patent US10981917 Publication Date 4/20/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Ribose-phosphate pyrophosphokinase 1 |
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| Name: | Ribose-phosphate pyrophosphokinase 1 |
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| Synonyms: | PRPS1 | PRPS1_HUMAN | Ribose-phosphate pyrophosphokinase I |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34836.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_156521 |
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| Residue: | 318 |
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| Sequence: | MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGC
GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG
ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTS
IADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG
ATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAI
RRTHNGESVSYLFSHVPL
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| BDBM493485 |
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| n/a |
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| Name | BDBM493485 |
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| Synonyms: | US10981917, Example 186 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H19BrN4O |
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| Mol. Mass. | 351.242 |
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| SMILES | Cc1c(Br)cnc2n(C\C=C\[C@H]3NCCC[C@@H]3O)cnc12 |r| |
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| Structure | 
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