| Reaction Details |
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 | Report a problem with these data |
| Target | Botulinum neurotoxin type A [1-429] |
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| Ligand | BDBM506813 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | BoNT/A LC429 Enzymatic assay |
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| Ki | 6.20±n/a nM |
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| Citation |  Jiao, G; Johnson, AT; O''Malley, S; Kim, SJ Hydroxamic acids comprising pyrazole moiety and uses thereof US Patent US11046652 Publication Date 6/29/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Botulinum neurotoxin type A [1-429] |
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| Name: | Botulinum neurotoxin type A [1-429] |
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| Synonyms: | BXA1_CLOBH | BoNT/A LC | Botulinum neurotoxin type A | bna | botA |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49198.33 |
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| Organism: | Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) |
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| Description: | P0DPI1[1-429] First 11 removed |
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| Residue: | 429 |
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| Sequence: | MPFVNKQFNYKDPVNGVDIAYIKIPNAGQMQPVKAFKIHNKIWVIPERDTFTNPEEGDLN
PPPEAKQVPVSYYDSTYLSTDNEKDNYLKGVTKLFERIYSTDLGRMLLTSIVRGIPFWGG
STIDTELKVIDTNCINVIQPDGSYRSEELNLVIIGPSADIIQFECKSFGHEVLNLTRNGY
GSTQYIRFSPDFTFGFEESLEVDTNPLLGAGKFATDPAVTLAHELIHAGHRLYGIAINPN
RVFKVNTNAYYEMSGLEVSFEELRTFGGHDAKFIDSLQENEFRLYYYNKFKDIASTLNKA
KSIVGTTASLQYMKNVFKEKYLLSEDTSGKFSVDKLKFDKLYKMLTEIYTEDNFVKFFKV
LNRKTYLNFDKAVFKINIVPKVNYTIYDGFNLRNTNLAANFNGQNTEINNMNFTKLKNFT
GLFEFYKLL
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| BDBM506813 |
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| n/a |
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| Name | BDBM506813 |
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| Synonyms: | US11046652, Example 1-7 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H26ClN3O3 |
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| Mol. Mass. | 379.881 |
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| SMILES | CCCCn1nccc1[C@@H](Cc1ccc(Cl)cc1)[C@@H](CC(=O)NO)OC |r| |
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| Structure | 
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