null

SMILES CCn1c(nc2cnccc12)-c1nonc1N

InChI Key InChIKey=UGHABJRZQKZAHP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 14032   

TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration exhibited towards MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z037P9PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against selected kinase DYRK1-alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FVNPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against selected kinase ROCK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FVNPubMed
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against selected kinase p70S6KMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FVNPubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against MSK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FVNPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14032(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)copy SMILEScopy InChI
Affinity DataIC50: 169nMAssay Description:Inhibitory concentration against selected kinase CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75FVNPubMed