null
SMILES Clc1ccc2c3[nH]c(nc3c3ccccc3c2c1)-c1c(cccc1C#N)C#N
InChI Key InChIKey=BVFLHOOKHPFDCT-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50227631
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of mPGES1 in IL-1beta-stimulated human A549 cells assessed as blockade of PGH2 to PGE2 conversion in presence of 50% fetal bovine serumMore data for this Ligand-Target Pair
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PGES2More data for this Ligand-Target Pair
TargetThromboxane-A synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of TX synthaseMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair