null
SMILES Clc1ccc2c3[nH]c(nc3c3ccccc3c2c1)-c1c(cccc1C#N)C#N
InChI Key InChIKey=BVFLHOOKHPFDCT-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50227631
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PGF synthase in IL1-beta treated human A549 cell microsome assessed as inhibition of PGF2alpha production after 1 min in presence of 50...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of mPGES1 in LPS-stimulated human whole blood assessed as inhibition of PGE2 productionMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsome assessed as inhibition of PGE2 production after 1 min in presence of 50% FBSMore data for this Ligand-Target Pair
TargetThromboxane-A synthase(Homo sapiens (Human))
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
Merck Frosst Center for Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of TX synthase in LPS-stimulated human whole blood assessed as inhibition of TXB2 productionMore data for this Ligand-Target Pair