null
SMILES CNC(=O)c1ccc2-c3sc(cc3CCOc2c1)C(=O)N(C)c1ccc(cc1Cl)C(=O)N(C)C
InChI Key InChIKey=GHUICRRPTSLMIY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50347076
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Genentech, Inc.
Curated by ChEMBL
Genentech, Inc.
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech, Inc.
Curated by ChEMBL
Genentech, Inc.
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant PI3Kalpha assessed as inhibition of PIP3 formation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Genentech, Inc.
Curated by ChEMBL
Genentech, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech, Inc.
Curated by ChEMBL
Genentech, Inc.
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant PI3Kalpha assessed as inhibition of PIP3 formation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Genentech, Inc.
Curated by ChEMBL
Genentech, Inc.
Curated by ChEMBL
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Genentech, Inc.
Curated by ChEMBL
Genentech, Inc.
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair