null

SMILES CNC(=O)c1ccc2-c3sc(cc3CCOc2c1)C(=O)N(C)c1ccc(cc1Cl)C(=O)N(C)C

InChI Key InChIKey=GHUICRRPTSLMIY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50347076   

LigandPNGBDBM50347076(CHEMBL1796761)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Apparent binding affinity to PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50347076(CHEMBL1796761)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Apparent binding affinity to PI3Kbeta using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50347076(CHEMBL1796761)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N57PubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Genentech, Inc.

Curated by ChEMBL
LigandPNGBDBM50347076(CHEMBL1796761)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N57PubMed
LigandPNGBDBM50347076(CHEMBL1796761)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant PI3Kalpha assessed as inhibition of PIP3 formation by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N57PubMed
LigandPNGBDBM50347076(CHEMBL1796761)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N57PubMed
LigandPNGBDBM50347076(CHEMBL1796761)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3Kalpha using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50347076(CHEMBL1796761)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of PI3Kbeta using PIP3 as substrate after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057GCQPubMed
LigandPNGBDBM50347076(CHEMBL1796761)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant PI3Kalpha assessed as inhibition of PIP3 formation by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N57PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Genentech, Inc.

Curated by ChEMBL
LigandPNGBDBM50347076(CHEMBL1796761)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N57PubMed
LigandPNGBDBM50347076(CHEMBL1796761)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N57PubMed