null
SMILES COCc1nc2c(cc(NC(=O)c3c(Cl)cccc3C(F)(F)F)cc2[nH]1)C(=O)Nc1cccc(Cl)c1C
InChI Key InChIKey=CWUCHFDQGIOAID-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50028856
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells using PGH2 as substrate incubated for 10 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells using PGH2 as substrate incubated for 10 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair