null

SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O

InChI Key InChIKey=YFGBQHOOROIVKG-FKBYEOEOSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50019056   

TargetMu-type opioid receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  0.650nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z42X1PubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  1.21nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC022NPubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  1.28nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC022NPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  6.90nMAssay Description:Displacement of radiolabeled DAMGO from mu opioid receptor in Hartley guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9RXFPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NGHPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZSPPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Inhibition of [3H]-DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GB231VPubMed
TargetMu-type opioid receptor(Danio rerio)
Instituto de Qu£mica Avanzada de Catalu£a (IQAC-CSIC)

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  684nMAssay Description:Displacement of [3H]DPN from zebrafish mu opioid receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50CJPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Compound was evaluated for its binding affinity against enkephalin mu receptor using [3H]-PL-017 as ligand in rat cerebrum in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50MVQ
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataEC50:  620nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NGHPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibitory potency against Opioid receptor mu 1 in longitudinal muscle preparation of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC0411PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataEC50:  304nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FXFPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Agonist activity at mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation by bi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1W34PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataEC50:  309nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FXFPubMed