null

SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O

InChI Key InChIKey=YFGBQHOOROIVKG-FKBYEOEOSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50019056   

TargetMu-type opioid receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  0.650nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z42X1PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of radiolabeled DPDPE-Cl from delta opioid receptor in Hartley guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9RXFPubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  1.21nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC022NPubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  1.28nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC022NPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z42X1PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NGHPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  6.90nMAssay Description:Displacement of radiolabeled DAMGO from mu opioid receptor in Hartley guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9RXFPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
UA 498 CNRS

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  7.30nMAssay Description:Inhibition of [3H]-DTLET binding torat brain membrane Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GB231VPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NGHPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Compound was evaluated for binding affinity towards mu-specific opiate receptor from combinatorial peptoid libraryMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26ZSPPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Inhibition of [3H]-DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GB231VPubMed
TargetOprd1b protein(Danio rerio)
Instituto de Qu£mica Avanzada de Catalu£a (IQAC-CSIC)

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Displacement of [3H]DPN from zebrafish delta 1b opioid receptor expressed in HEK293 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50CJPubMed
TargetNociceptin receptor(Cavia porcellus)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  277nMAssay Description:Displacement of radiolabeled NalBzOH from kappa3 opioid receptor in Hartley guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9RXFPubMed
TargetMu-type opioid receptor(Danio rerio)
Instituto de Qu£mica Avanzada de Catalu£a (IQAC-CSIC)

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  684nMAssay Description:Displacement of [3H]DPN from zebrafish mu opioid receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR50CJPubMed
TargetNociceptin receptor(MOUSE)
McGill University

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7FWBPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z42X1PubMed
TargetNociceptin receptor(MOUSE)
McGill University

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7FWBPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi:  4.47E+3nMAssay Description:Displacement of radiolabeled U69593 from kappa1 opioid receptor in Hartley guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9RXFPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NGHPubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Compound was evaluated for its binding affinity against enkephalin mu receptor using [3H]-PL-017 as ligand in rat cerebrum in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50MVQ
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataEC50:  620nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NGHPubMed
TargetMu-type opioid receptor(GUINEA PIG)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibitory potency against Opioid receptor mu 1 in longitudinal muscle preparation of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC0411PubMed
TargetDelta-type opioid receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibitory potency against delta Opioid receptor delta 1 in longitudinal muscle preparation of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC0411PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataEC50:  304nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FXFPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataEC50:  1nMAssay Description:Agonist activity at human recombinant delta opioid receptor expressed in HEK293 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RPSPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataEC50:  1nMAssay Description:Agonist activity at human recombinant delta opioid receptor expressed in human HEK293 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H995MXPubMed
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in presence of NaCl (100 mM)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4XZNPubMed
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Compound was tested for its ability to displace [3H]naloxone from Opioid receptors in absence of NaClMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4XZNPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataEC50:  47nMAssay Description:Agonist activity at human cloned delta opioid receptor assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7NGHPubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for its binding affinity against enkephalin kappa receptor using [3H]-U-69,593 as ligand in guinea pig cerebrum in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50MVQ
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1HDVPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Agonist activity at mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation by bi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1W34PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Agonist activity at delta receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation by biolum...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1W34PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Chiron Corporation

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataEC50:  309nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FXFPubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
UA 498 CNRS

Curated by ChEMBL
LigandPNGBDBM50019056((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Compound was evaluated for its binding affinity against enkephalin delta receptor using [3H]-DPDPE as ligand in rat cerebrum in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50MVQ