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SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=YFWXFHNZGKNDBC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50009718   

TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7VXH
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Displacement of the specific binding ligand [125I]-Sar1,Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membrane.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92B6P
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:In vitro binding affinity of the compound for angiotensin II AT1 receptor in rabbit aortaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1HZ3PubMed
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]-Sar1-Ile8-A II at the rabbit aorta angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55MKHPubMed
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibitory activity was evaluated against Angiotensin II receptor, type 1 in rabbit aortaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P3299PubMed
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.540nMAssay Description:In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26M35X0PubMed
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.540nMAssay Description:In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F6PPubMed
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NP2524PubMed
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.540nMAssay Description:Displacement of [1251][Sar1,IIe8]AII from rabbit aorta Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J1027WPubMed
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73DPF
TargetType-1 angiotensin II receptor(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Compound was tested for in vitro for AII receptor antagonistic activity in bovine adrenal cortex.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F18ZN4
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Binding affinity to angiotensin AT1 receptor in rabbit aortic ringsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G3TPubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB463JPubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at angiotensin 1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95PHPubMed
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:In vitro binding affinity of the compound towards Angiotensin II type 1-AT1 receptor determined as its ability to displace 125I-Sarl,Ile8-AII from th...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q12
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50009718(2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Angiotensin II receptor type 1 in rabbit aorta binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z15GM