null
SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
InChI Key InChIKey=YFWXFHNZGKNDBC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 31 hits for monomerid = 50009718
Affinity DataKi: 0.450nMAssay Description:Binding affinity against angiotensin II receptor from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Binding affinity against Angiotensin II receptor, type 1 using [125I]Sar-Ile8-AII in rat liver membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 in rabbit ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of the specific binding ligand [125I]-Sar1,Ile8-AII from Angiotensin II receptor, type 1 in rabbit aorta membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:In vitro binding affinity of the compound for angiotensin II AT1 receptor in rabbit aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]-Sar1-Ile8-A II at the rabbit aorta angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibitory activity was evaluated against Angiotensin II receptor, type 1 in rabbit aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro binding affinity of the compound for angiotensin II AT2 receptor in rat midbrainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Displacement of [1251][Sar1,IIe8]AII from rabbit aorta Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [1251][Sar1,IIe8]AII from rat midbrain angiotensin II (AT2) receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro antagonist activity against angiotensin II receptor type 2 in rat midbrain using [125I]-Sar,Ile AII.More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Binding affinity for rat angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro binding affinity of the compound towards Angiotensin II receptor, type 2 determined as its ability to displace 125I-Sarl,Ile8-AII from the r...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from Angiotensin II receptor, type ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro binding affinity determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from AT2 receptor in rat midbrain m...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of rat midbrain angiotensin II type 2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Compound was tested for in vitro for AII receptor antagonistic activity in bovine adrenal cortex.More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Binding affinity to angiotensin AT1 receptor in rabbit aortic ringsMore data for this Ligand-Target Pair
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
The M. S. University of Baroda
Curated by ChEMBL
The M. S. University of Baroda
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Binding affinity to angiotensin AT2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer Inc.
Curated by ChEMBL
Pfizer Inc.
Curated by ChEMBL
Affinity DataEC50: >2.00E+4nMAssay Description:Partial agonist activity at human PPARgamma-LBD/Gal4 DNA binding domain by transactivation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at angiotensin 1 receptorMore data for this Ligand-Target Pair
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Exploratory Chemistry Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Exploratory Chemistry Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Binding affinity towards Angiotensin receptor from rabbit aortaMore data for this Ligand-Target Pair
TargetType-1/Type-2 angiotensin II receptor(Homo sapiens (Human))
Exploratory Chemistry Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Exploratory Chemistry Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Displacement of monoiodinated angiotensin II from guinea-pig adrenal gland angiotensin II receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:In vitro binding affinity of the compound towards Angiotensin II type 1-AT1 receptor determined as its ability to displace 125I-Sarl,Ile8-AII from th...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Angiotensin II receptor type 1 in rabbit aorta binding assayMore data for this Ligand-Target Pair