null

SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)c2ccccc12

InChI Key InChIKey=UEJJHQNACJXSKW-UHFFFAOYSA-N

PDB links: 24 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50070114   

TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute for Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)copy SMILEScopy InChI
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of MANT-uracil binding to wild-type Magnetospirillum gryphiswaldense CRBN isoform 4 by FRET assayMore data for this Ligand-Target Pair
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute for Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)copy SMILEScopy InChI
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of MANT-uracil binding to wild type Magnetospirillum gryphiswaldense cereblon isoform 4 by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))TBA
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)copy SMILEScopy InChI
Affinity DataKi:  8.51E+3nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence in pr...More data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))TBA
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)copy SMILEScopy InChI
Affinity DataKi:  2.27E+4nMAssay Description:Inhibition of MANT-uracil binding to human CRBN (delta 1 to 315) by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair