null

SMILES COC(=N)c1nc2ccc3ncnc(Nc4ccc(OC)cc4F)c3c2s1

InChI Key InChIKey=RYBNARZBIXTFJS-UHFFFAOYSA-N

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 246383   

TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM246383(US9446044, 69)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CLK1 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))TBA
LigandPNGBDBM246383(US9446044, 69)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CLK4 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
LigandPNGBDBM246383(US9446044, 69)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of DYRK2 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
LigandPNGBDBM246383(US9446044, 69)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of DYRK2 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM246383(US9446044, 69)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))TBA
LigandPNGBDBM246383(US9446044, 69)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM246383(US9446044, 69)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))TBA
LigandPNGBDBM246383(US9446044, 69)copy SMILEScopy InChI
Affinity DataIC50: 80nMMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM246383(US9446044, 69)copy SMILEScopy InChI
Affinity DataIC50: 111nMMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM246383(US9446044, 69)copy SMILEScopy InChI
Affinity DataKd:  7.60nMMore data for this Ligand-Target Pair