null

SMILES CNc1nc2sc(nc2c2n(C)cnc12)-c1ccccc1

InChI Key InChIKey=RINVSNFRQRWTCD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 28545   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28545(N,12-dimethyl-4-phenyl-5-thia-3,7,10,12-tetraazatr...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB804MPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28545(N,12-dimethyl-4-phenyl-5-thia-3,7,10,12-tetraazatr...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMT: 2°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB804MPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28545(N,12-dimethyl-4-phenyl-5-thia-3,7,10,12-tetraazatr...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of IKK1-catalyzed phosphorylation of GST-tagged IkappaBalpha fusion protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SX8PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28545(N,12-dimethyl-4-phenyl-5-thia-3,7,10,12-tetraazatr...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SHGPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28545(N,12-dimethyl-4-phenyl-5-thia-3,7,10,12-tetraazatr...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of IKK2-catalyzed phosphorylation of GST-tagged IkappaBalpha fusion protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SX8PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28545(N,12-dimethyl-4-phenyl-5-thia-3,7,10,12-tetraazatr...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of IKK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5GZDPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM28545(N,12-dimethyl-4-phenyl-5-thia-3,7,10,12-tetraazatr...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of IKK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5GZDPubMed