null

SMILES CN(C)c1ccnc2sc3c(ncn(-c4ccc(Cl)cc4)c3=O)c12

InChI Key InChIKey=PCDABTQQAJSLPA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50177076   

TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177076(3-(4-Chloro-phenyl)-9-dimethylamino-3H-pyrido[3',2...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8XX0PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177076(3-(4-Chloro-phenyl)-9-dimethylamino-3H-pyrido[3',2...)copy SMILEScopy InChI
Affinity DataKi:  1.03E+3nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8XX0PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177076(3-(4-Chloro-phenyl)-9-dimethylamino-3H-pyrido[3',2...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of rat mGluR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987VMPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177076(3-(4-Chloro-phenyl)-9-dimethylamino-3H-pyrido[3',2...)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8XX0PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177076(3-(4-Chloro-phenyl)-9-dimethylamino-3H-pyrido[3',2...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8XX0PubMed