Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50177076'
TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177076(3-(4-Chloro-phenyl)-9-dimethylamino-3H-pyrido[3',2...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8XX0PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177076(3-(4-Chloro-phenyl)-9-dimethylamino-3H-pyrido[3',2...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of rat mGluR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V987VMPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177076(3-(4-Chloro-phenyl)-9-dimethylamino-3H-pyrido[3',2...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8XX0PubMed