null

SMILES OC(=O)[C@H]1CC[C@H]2CN[C@@H]([C@@H]12)C(O)=O

InChI Key InChIKey=LXFIOZSRMYVFHN-YTLHQDLWSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50180145   

TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50180145((1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarb...)copy SMILEScopy InChI
Affinity DataKi:  4.60E+4nMAssay Description:Activity against human EAAT3 transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86WBPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Berne

Curated by ChEMBL
LigandPNGBDBM50180145((1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarb...)copy SMILEScopy InChI
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081NRPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Berne

Curated by ChEMBL
LigandPNGBDBM50180145((1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarb...)copy SMILEScopy InChI
Affinity DataKi:  5.20E+4nMAssay Description:Activity against human EAAT2 transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86WBPubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50180145((1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarb...)copy SMILEScopy InChI
Affinity DataKi:  1.27E+5nMAssay Description:Activity against human EAAT1 transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86WBPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50180145((1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarb...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+6nMAssay Description:Activity against mGluR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86WBPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50180145((1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarb...)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+6nMAssay Description:Activity against mGluR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM86WBPubMed