null
SMILES NC(=O)c1ccc(cc1)-c1cc(cnc1N)-c1scc2OCCOc12
InChI Key InChIKey=AWUXFIAHZKNRJF-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50309182
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Inhibition of CHK2 in human HT29 cells assessed as blockade of etoposide-induced DNA damage-activated enzyme phosphorylation by Western blotingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Institute of Cancer Research
Curated by ChEMBL
Institute of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair