Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk2' and Ligand = 'BDBM50309182'
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309182(4-(2-Amino-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-...)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309182(4-(2-Amino-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-...)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of CHK2 in human HT29 cells assessed as blockade of etoposide-induced DNA damage-activated enzyme phosphorylation by Western blotingMore data for this Ligand-Target Pair