null

SMILES OP(O)(=O)C(Nc1ncnc2sc(cc12)-c1ccccc1)P(O)(O)=O

InChI Key InChIKey=RKCFLTMAEZJQBB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50520642   

TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50520642(CHEMBL2347861 | US11279719, Example C-10)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of human N-terminal His6-tagged GGPPS expressed in Escherichia coli BL21(DE3) using [14C]-IPP and FPP as substrates after 10 mins by scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8HWFPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50520642(CHEMBL2347861 | US11279719, Example C-10)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The assay was based on a literature procedure (Kavanagh, et al. J. Biol. Chem., 2006, 281, 22004-22012) with minor modifications. All assays were run...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ1470US Patent
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
McGill University

Curated by ChEMBL
LigandPNGBDBM50520642(CHEMBL2347861 | US11279719, Example C-10)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human FPPS using [14C]-IPP and FPP as substrates after 10 mins by scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8HWFPubMed