null

SMILES NC(=O)C[C@H]1COc2cc(F)cc(F)c2N1C(=O)c1ccc2OCC(=O)Nc2c1

InChI Key InChIKey=FDNJKRDYTFEETA-NSHDSACASA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50531568   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-aldosterone to human mineralocorticoid receptor LBD by radiometric binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataKi:  1.26E+3nMAssay Description:Binding affinity to recombinant human GR LBD by fluormone GS red-fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataIC50: 631nMAssay Description:Antagonist activity at gal4-fused human mineralocorticoid receptor LBD expressed in UAS-MR-bla HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Modulation activity at human mineralocorticoid receptor in human EA.hy926 cells assessed as induction of nuclear translocation of mineralocorticoid r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Antagonist activity at full length human mineralocorticoid receptor expressed in human U2OS cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed
TargetMineralocorticoid receptor(RAT)
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Modulation activity at human mineralocorticoid receptor in human EA.hy926 cells assessed as blocking of nuclear translocation of mineralocorticoid re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed