Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Mineralocorticoid receptor' and Ligand = 'BDBM50531568'
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-aldosterone to human mineralocorticoid receptor LBD by radiometric binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed
TargetMineralocorticoid receptor(RAT)
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Antagonist activity at full length human mineralocorticoid receptor expressed in human U2OS cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataIC50: 631nMAssay Description:Antagonist activity at gal4-fused human mineralocorticoid receptor LBD expressed in UAS-MR-bla HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Modulation activity at human mineralocorticoid receptor in human EA.hy926 cells assessed as blocking of nuclear translocation of mineralocorticoid re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pharmaron-Beijing Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50531568(CHEMBL4455600)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Modulation activity at human mineralocorticoid receptor in human EA.hy926 cells assessed as induction of nuclear translocation of mineralocorticoid r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RP6PubMed