null
SMILES Oc1ccc(CN2C(=O)C(=O)c3cc(ccc23)S(=O)(=O)N2CCC[C@H]2COc2ccccc2)cc1
InChI Key InChIKey=KYJSQQPQAAKFQY-IBGZPJMESA-N
PDB links: 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 10334
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataIC50: 13.5nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataIC50: 13.5nMpH: 7.4 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
University Hospital of the Westfälische Wilhelms-Universität
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Inhibition of caspase 3More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of caspase 6More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of caspase 1More data for this Ligand-Target Pair
Affinity DataIC50: 52.7nMAssay Description:Inhibition of caspase 7More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of caspase 8More data for this Ligand-Target Pair